Diagnostic Control Study Of Full-field Digital Mammography And Color Doppler Ultrasonography In The Breast Benign And Malignant Diseases

PurposeTo evaluate the diagnostic value and clinical significance of complete digital mammography and color Doppler ultrasonography in benign and malignant mammary lesions.MethodsThe outpatients and inpatients with breast lesions in the first affiliated hospital of China medical university between June, 2006 and December, 2006 were reviewed. In a total of 100 patients without any history of biopsy, physical therapy, radiotherapy or operation, the complete digital mammography and color Doppler ultrasonography were both performed, and the pathologic diagnosis was obtained.ResultsThe pathologic diagnosis showed 57 benign and 43 malignant findings. Complete digital mammography made a diagnosis with accuracy of 45 cases in benign findings and 40 in malignant. The number was 50 and 35 for color Doppler ultrasonography respectively. The sensitivity, specificity, positive predictive value, negative predictive value, false-positive rate, and false-negative rate of malignant lesions were 93.02%, 78.95%, 76.92%, 93.75%, 21.05%, and 6.98% for complete digital mammography; 81.40%, 87.72%, 83.33%, 86.21%, 12.28%, and 18.6% for color Doppler ultrasonography; 95.35%, 71.93%, 71.93%, 95.35%, 28.07%, and 4.65% for combined strategy respectively. Early carcinoma was found in 7 cases, and intraductal carcinoma in 1 case, intraductal papilloma with malignant transformation in 2 cases, intraductal carcinoma with early invasion in 2 cases, mastopathy with early malignant transformation in 1 case, mastopathy with severe atypical hyperplasia in 1 case respectively. The complete digital mammography detected all these cases and the color Doppler ultrasonography missed 3 cases.ConclusionComplete digital mammography and color Doppler ultrasonography had diagnostic value in detecting mammary lesions, each had advantage when used separately, and combined using could elevate sensitivity and negative predictive value, and could decrease the false-negative rate. Complete digital mammography was superior to color Doppler ultrasonography in detection rate for malignant lesions, early carcinoma, and microcalcification. Color Doppler ultrasonography had a higher detection rate than complete digital mammography in benign mammary lesions.