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Optical Coherence Tomography Of Macular After Vitrectomy With Silicone Oil Tamponade

Posted on:2008-01-02Degree:MasterType:Thesis
Country:ChinaCandidate:Y QinFull Text:PDF
GTID:2144360215989106Subject:Ophthalmology
Abstract/Summary:PDF Full Text Request
Objective:To assess prospectively the features of the macular after vitrectomy with siliconeoil tamponade by analyzing whether silicone oil affects OCT measurements andwhether a statistical correlation exists between postoperative BCVA and revealthickness measured by OCT; To find the reason of incomplete vision in patientswho undergone anatomically successful surgery.Meathods:We performed Germany Zeiss-Humphery OCT 2000 on 60 eyes of 42 healthyvolunteers and 37 eyes of 37 patients who had undergone PPV using silicone oil(5,000cST) for retinal reattachment from October 2005 to January 2007 at Tian JinMedical University Eye Center. The postoperative follow-up period is three months.After each patient was examined carefully, all patients were offered silicone oiltamponade. Phacoemulsification and aspiration for cataract with intraocular lenimplantation was performed on 20 patients before the vitreous surgery or at the timeof vitreous surgery. The postoperative examination included BCVA, intraocularpressure measurement using Canon, slit-lamp biomicroscopy, binocular indirectophthalmoscopy, fundus photography and OCT.The patients' pupils were fully dilated with topical tropicamide, and the funduswas scanned with radial scans crossing the central fovea, then six optical coherencetomograms were obtained. Retinal thickness was computed automatically from each tomogram. Macular thickness was displayed geographically as a false-colortopographic map and was reported numerically as averages in each of nine regions.The scan length was usually 4.0 mm. Postoperative OCT images were then obtainedthrough silicone oil tamponade after 2 weeks, 1 month, 2 months, 3months.Results:The mean±SD of central foveal is 151.5±11.1μm in the healthy. After 3 monthspostoperatively, all patients have achieved retinal reattachment anatomically, BCVAis from 0.01 to 0.5, the mean±SD of BCVA is 0.21±0.16, the macular foveal thicknessis from 116μm to 576μm, the mean±SD of foveal thickness is 261.03±82μm. There isnegative linear correlation between the mean macular foveal thickness and BCVA instatistic(P=0.006<0.05, r=-0.464). In 37 following patients, OCT finds 5 eyes ofnormal macular foveal thickness (13.51%); 1 eye ofmacular thinning (2.70%); 31eyes of macular edema(83.78%); to configuration, 7 eyes of cystoid macularedema(22.58%), 6 eyes of retina spongy thickening(19.35%), 2 eyes of serous retinaldetachment (6.45%), 16 eyes of macular epiretinal membranes with edema (51.61%),to macular thickness, 19 eyes of low macular edema (201μm~300μm), 8 eyes ofmoderate macular edema (301μm~400μm), 4 eyes of bad macular edema(>400μm).Conclusion:The configuration of macular in the early postoperative period after pars planavitrectomy using OCT through silicone oil was evaluated; There is negative linearcorrelation between the mean macular foveal thickness and the best-corrected visualacuity in statistic; Macular edema is a common finding on optical coherencetomograms in eyes with incomplete visual recovery after anatomically successfulsurgery. Next is macular epiretinal membrane. The last is macular thinning.In a word, OCT is a useful technique for quantifying macular thickness inpatients who undergone PPV, assessing poor postoperative visual acuity and finding diseases undetected at clinical examinations. The topographic mapping protocolprovides geographic information on macular thickness that is objective and intuitive.We can follow progress and prognosis ofmacular edema with retinal topographic map.
Keywords/Search Tags:Vitrectomy with silicone oil tamponade, Optical coherence tomography, Macular thickness, Retinal topographic map, Macular epiretinal membranes, Macular edema
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