The Clinical Studies On Glucose Metabolic Disorders Secondary To Chronic Hepatitis B

Objective: By the regularity and remedial study on Glucose Metabolic Disorders secondary to Chronic Hepatitis B, Systematically surveying and analying its occurrence, pathogenesis, syndrome features and related factors. To observe GanRongTang's clinical efficacy of GanRongTang's ,hoping the evidence-based significance of a breakthrough to the disease by TCM.Methods: Regularity Study To sum up the incidence rate, Lesions,correlation factor analysis,to approach the pathogenesis regularity of TCM,to establish the ifferentiation of symptoms and signs for classification of syndrome,to formulate therapeutic principle of the differentiation of symptoms and signs. Remedial Study According to the ratio 6:1, to select 32 patients from all the 171 regularity study patients trabantly,and to run the regularity study simultaneously. GanRongTang play the anction of invigorating spleen and soothing liver, qingre, damp elimination, dissipate phlegm, promoting blood flow, disintoxication, PO dosis quotidie,the time of therapy is 2 months. To define the bland diet Strictly,to observe the effection on the liver function, glucose metabolism and TNF-α.Results: By Stepwise Linear Regression , the degree of glucose metabolic disorders of Chronic Hepatitis B has the noticeable relations to wrong medication history, eating habit, TNF-α,BMI, AST,ALT,liver imageology, The total effective rate is 65.6%, symptom effective rate is 100%, GanRongTang obviously ameliorat the liver function, Glucose Metabolic ,TNF-αand the liver imageology(P<0.01orP<0.05).Conclusion: Glucose metabolic disorders secondary to chronic hepatitis B virus invasion in the early stage of liver disease. The unscientific living and eating habits, improper treatment can promote the progress of epatogenic diabetes(HD). The treatment of invigorating spleen and soothing liver, qingre, damp elimination, dissipate phlegm, promoting blood flow, disintoxication can effectively amendment the liver function, obviously reverse the secondary glucose metabolic disorders.