| Objective: To investigate the therapeutic effects of endoscopic retrograde cholangiopancreatography(ERCP) and endoscopic sphincterotomy(EST) for cholangiopancreatic disease. Methods: 66 patients with cholecystopancreatic disease underwent ERCP, 2 cases of them underwent ERCP twice, the subsequent EST to remove the stones and to amputate papilla of Vater. Meanwhile in order to analyse the diagnostic and therapeutic effects of ERCP, 44 patients with bile ducts obstruction performed magnetic resonance cholangiopancreatography(MRCP) in compare. Discuss: how to reduce the occurrence of complication, to provide managements of prevention and treatment associated with the ERCP-induced complications. Results: The most frequent cause was cholelithiasis (41.7%),of them stricture of bile duct (27.3%) was the second frequent cause, constrictive papillitis was 3.09%, cancer of ampullae was 3.0%,chronic pancreatitis was 3.0%, periampullary diverticular was 1.5%, endoscopic retrograde pancreatography was 1.5%. These cases underwent ERCP to make the diagnosis of cholecystopancreatic disease and the subsequent EST to remove the stones,to open papilla of Vater. Only 4 patients of them has got the complications including mild pancreatitis in 1 patient, hyperamylasemia in 1 patient ,gastrointestinal bleeding in 2 patient .Patients with these complications were all cured. Conclusion: The advantage of ERCP is micro-invasive, safe and efficient. ERCP has significant value in diagnosing and treating in cholecystopancreatic disease.
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