Serum Level Of Mannose-binding-lectin (MBL) In Children With Recurrent Respiration Tract Infection

Objective: To establish the children's reference range of serum level of mannose binding lectin(MBL)serum levels,and to find the relationship between MBL and recurrent respiratory tract infections (RRTI). Methods: Serum levels of MBL were determined in 92 healthy children and 77 recurrent respiratory tract infection of children,then compared with the levels of MBL between groups. Results: The evaluation in healthy children and children with RRTI were 3.34±2.09μg/ml and 2.17±1.24μg/ml, respectively. There was a significant difference (P<0.05). Conclusion: There is a interrelation between the lower level of MBL and the RRTI. The lower level of MBL may be a cause of RRTI.