| Heart disease is a serious disease to human health, so the inspection and evaluation of cardiac function is an important issue in the clinical heart disease. In the heart function tests domain , invasive examination includes X-ray left ventricular angiography , radionuclide angiography of low spatial resolution and radioactive damage to the left ventricle (radionuclide blood-pool imaging) examination, and non-invasive ones, including echocardiography , PET and magnetic resonance imaging (MRI) technology. Echocardiography is still the most commonly used clinical evaluation means of cardiac function. However, the results excessive reliance on the technical of inspection operation and image quality of the acoustic window. Echocardiography examination of the left ventricular volume calculation is based on the geometry model, the left ventricular model is a half ellipsoid, but volume calculation is obvious error such as hypertrophic obstructive cardiomyopathy and asymmetric patterns left ventricular cavity. Coronary angiography is an important methods in the diagnosis of coronary artery disease and understanding of the coronary vascular tree, but do not reflect changes in cardiac function and pathological physiological conditions. 20lTI radionuclide imaging of myocardial perfusion has been relatively mature, but coronary artery disease involving count, location, etc. will affect the accuracy of detection. But it is radioactive, and more expensive, and hard to universal. Since the early 1980's , MRI began to used to exam the heart function. With the applications of the heart gated control technology, the emergence of various rapid sequence, as well as the upgrading of computer software, MRI examination of left ventricular function has become a fully mature technology, and a large number of studies show that left ventricular function examination using MRI film technology has become standards in all the cardiac function tests.Healthy adult and 172 patients with myocardial ischemia and myocardial infarction patients are examined with MR FIESTA myocardial contractile function and myocardial perfusion, assessing the clinical value of magnetic resonance FIESTA technology in myocardial contractile function and MRI myocardial perfusion and myocardial contractile function in myocardial viability. FIESTA sequence is mainly used in collection of short-axis and long-axis throb dynamic cardiac MR film. Fast gradient echo sequence is mainly used to collect myocardial perfusion MR image of first-pass phase of. Flip gradient echo sequence is mainly used to collect delayed 60 minutes myocardial perfusion MR image. By measure the data of myocardial ischemia,myocardial infarction patients and healthy comparison, we determine whether myocardial movement and myocardial blood flow become weak. Results of left ventricular systolic wall and the rate of thickening are treated with statistical, , the range of myocardial motion is 7.89±1.02mm thickening was 93.8±37.6%. Myocardial perfusion parameters adopt preliminary studies, the low signal intensity area of first-pass myocardial perfusion (105.2±32.1) , the myocardial signal intensity around low perfusion areas (166.7±53), signal intensity (153.12±46.7) around area myocardial signal intensity (121.3±43.9). Slope of time-intensity curve adopt 2.040±0.395 as reference values. 100 cases examined FIESTA myocardial function examination of myocardial ischemia group showed weakened movement myocardial lesions compared with the normal group (P <0.01), and in 82 cases ,peak and peak time of signal intensity curve was longer in than the normal group, slope decreases. 18 cases of weakened movement myocardial lesions showed normal myocardial perfusion myocardial blood flow. All patients with delayed reperfusion myocardial signal intensity lesions showed no significant difference (P <0.01). AMI myocardial infarction showed weakened position movement, some cases showed reverse movement, a statistically significant with the normal group and myocardial ischemia group, P <0.01. The first-pass phase perfusion imaging of myocardial infarction showed no enhancement or strengthen low, and the signal was significantly lower than normal, but it was significantly higher than normal myocardial in delayed scanning . Slope of time-intensity curve decreases, P <0.01. Compared with the normal group, myocardial signal and slope in myocardial ischemia and myocardial infarction were statistically significant P <0.01, but it is not statistically significant compared myocardial ischemia with myocardial infarction group, (P> 0.05). Results of MRI myocardial viability examination and the CAG inspection are very high correlation in myocardial ischemia and myocardial infarction group.MRI FIESTA cardial function technology can precise analysis the ventricular wall motion, thicken and thickening, and diagnosis abnormal myocardial motion segments sensitivity. MR first-pass myocardial perfusion together with delayed phase can discriminate viable, infarct and normal ones. Technology of combining MRI FIESTA cardiac function with myocardial perfusion is non-invasive, non-radioactive, security checks, high spatial resolution and signal noise ratio, can discriminate not only viability myocardial but also stunned myocardium, hibernating myocardium. It provides large help for clinical and is a has irreplaceable advantages.At present, higher cost of MR cardiac function inspection is limit in its wider use . But as standard in left ventricular systolic function, in cardiac disease, aneurysm diagnosis and other ,when cardiac systolic function need special accurate evaluation, FEISTA technology provide a high time and spatial resolution imaging and accurate myocardial thickness, shape and ventricular volume, ventricular wall motion and function information and so on. Because of three-dimensional imaging, it provide more checks and other unique diagnostic information, above on the traditional non-invasive detection methods such as UGG, left ventricular angiography and radionuclide. It can redeem inadequate of other imaging examination in the diagnosis of cardiomyopathy. It is an effective method for the diagnosis of hypertrophic and dilated cardiomyopathy, playing an irreplaceable role. With the mature of MR left ventricular systolic function, research of right ventricular function evaluation has just started, we believe that the MR FIESTA cardiac function will have more broad application prospects. |
PDF Full Text Request