| Objectives:The purpose of this study were: (1)to describe the primarily epidemiology status of the intracranial tumors(brain tumors),including the prevalence rate,incidence rate and mortality rate in patients with intracranial tumors;(2) to quantificationally evaluate QOL of brain tumors patients and to discuss its impact factors.Methods : The study was conducted in Ma'anshan city,including Huashan district,Yushan district and Jinjiazhuang district. Questionnaire cited on SF-36 instrument and on determinants of QOL were used to make surveys on 66 primary intracranial tumors patients who were alive between Jan 1st,2006 and Dec 31,2006 and 66 health subjects.Results: 1.The prevalence rate,incidence rate and mortality rate in patients with intracranial tumors was respectively about 18.2/100000, 5.0/100000and 3.4/100000 in Ma'anshan city from Jan 1st,2006 and Dec 31,2006. 2.The QOL of the brain tumors patients:(1) Every domain and total SF-36 subscales of brain tumors patients were significantly lower than those in the health subjects group. The ascending order of dimensional subscales was GH,RP,RE,VT,PF,BP,MH and SF. (2)The scores of VT and SF domain were lower in female patients than in male patients.(3)The scores of PF,BP and SF domain were significantly higher in patients at the age of below 50 than those above 50.(4)There was no significant difference in any dimensional subscales in patients at aspect of marriage.(5)There were significant difference in PF and VT dimensional subscales in educational level in patients. LSD-t analysis indicated that the score of PF domain was lower in illiterate group than in primary school group, high school group and above college or university group; the score of RP domain was lower in primary school group than in high school group, the score of BP domain was lower in illiterate group than in high school group and above college or university group; the score of GH domain was lower in illiterate group and primary school group than in high school group; the score of VT domain was lower in illiterate group than in high school group and above college or university group, and lower in primary school group than in high school group, and lower in junior school group than in high school group and above college or university group; the score of SF domain was lower in illiterate group than in high school group; the score of RE domain was lower in illiterate group than in high school group, and lower in junior school group than in high school group and above college or university group; there was no significant difference in MH dimensional scores.(6) There was significant difference in VT dimensional subscales at aspect of month income of patients. LSD-t analysis indicated that the score of PF domain was significantly lower in≤200yuan group than in 1001-2000yuan group; the score of BP domain was significantly lower in 201-500yuan group than in 1001-2000yuan group and above 2000yuan group; the score of VT domain was significantly lower in≤200yuan group than in above 2000yuan group,and lower in 201-500yuan group than in 1001-2000yuan group and above 2000yuan group, and lower in 501-1000yuan than in above 2000yuan group. (7) The scores of PF and RP domain was higher in'half at public expense/ at public expense'group than in'all at one's own expenses'group. (8) Every domain and total SF-36 subscales in different pain degree patients were significantly lower in'severe group'than in'light group'.(9) The scores of seven domain except for PF domain were significantly difference in two variables,including'whether always depressive but don't want to express or not'and'whether always oppress his agony but don't pour out or not'. (10) The scores of RE and MH domain were significantly lower in'always be excess tense and worrying group' than in the control group. The scores of six domain except for PF and RE domain were significantly lower in'mood always be depressed and gloomy group'than in the control group.(11)Multivariate linear stepwise regression analysis indicated that 5 variables had important impact on QOL of brain tumors: educational level, pain dergree, always depressive but don't want to express , always oppress his agony but don't pour out, and mood always be depressed and gloomy.Conclusions:1. The prevalence rate and incidence rate in this study were significantly higher than the statistical datas, and mortality rate was a little lower than that. 2.Total life quality of patients with brain tumors worsened generally. The QOL of brain tumors patients wasn't affected by their marriage status. Gender,age and medical insurance status have impact on 1-3 domains of QOL. Much or little of family support is likely to be an impact factor of QOL in brain tumor patients. Educational level, pain dergree, character (always depressive but don't want to express , always oppress his agony but don't pour out), and mood always be depressed and gloomy tend to be the important factors that influence the QOL of brain tumor patients.
|
PDF Full Text Request