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Anti-double Stranded DNA Antibody And Upus Nephritis Pathologic Type And Kidney Injure Of Clinical Analysis

Posted on:2009-04-16Degree:MasterType:Thesis
Country:ChinaCandidate:J Y YangFull Text:PDF
GTID:2144360242499720Subject:Dermatology and Venereology
Abstract/Summary:PDF Full Text Request
Objective Pass to resist the review sexually transmitted disease of the dsDNA antibody an example to check against analysis, resist dsDNA antibody fixed amount a measurement by ELASA method in the meantime, it result and the kidney pathologic type and kidney injure of related circumstance.Investigate the relation that the anti- dsDNA antibody and lupus kidney blaze thus and further.Methods The serum which collects medicine department university in Xinjiang first a subsidiary hospital March, 2006 to March, 2008 SLE inpatient is to sieve serum.The case selects standard to match:(1)Match American rheumatism association(ACR) to draw up in 1982 of of SLE diagnosis standard, and immunology check ANA drop degree≥1:100;(2) Not the companion has an infection perhaps other oneself immunity disease.Is divided into the sufferer who allly brings into the anti- dsDNA antibody male set and the anti- dsDNA antibody feminine gender set, compares them a kidney a being burning at the lupus of the kidney live the covariance of of check and kidney damage to learn meaning, select by examinations the anti- dsDNA antibody male set in the meantime, as to it's the fixed amount measurement, its number and kidney live the covariance of of check the pathologic type and kidney damage to learn meaning.Conclusion①LN clinical performance and pathology change the existence certain relativity.②The clinical performance of the LN is diverse vivid, in response to close observation LN the sufferer wet egg white, kidney achievement circumstance.③The LN sufferer of anti- dsDNA antibody is clinical symptom complications be diverse, with anti- dsDNA antibody male set sufferer's comparison activity, kidney injure more heavy.The anti- dsDNA antibody male sufferer kidney injure more heavy, should cause the clinical doctor's high vigilance.④The anti- dsDNA antibody metered level and kidney injure degree and the kidney pathologic type severity degree can the unbalance, the anti- dsDNA antibody metered level and kidney injure degree and kidney a pathologic type irrelevant.
Keywords/Search Tags:Anti - dsDNA antibodies, Lupus nephritis, Pathology, Enzyme-Linked Immunosorbent Assay(ELISA)
PDF Full Text Request
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