Clinical Study On Effectiveness Of Essential Hypertension And Influence On Biochemical Parameters Treated By The Therapeutic Method Of Eliminating Phlegm, Tranquilizing And Calming Wind

Essential hypertension(EH)is a disease whose incidence is highest in Cardiovascular Diseases(CVD).It is reported that only hypertension can make 30 percent patients of CVD in the world die.In the past few years, the incidence of EH has climbed year after year.At now,there are about 160 million patients of EH in our country.Hypertension and its correlated diseases not only influence patients' living quality,and brings heavy burden on family and society,but also brings horrifying cost of medical treatment.How to control and treat hypertension effectively has been an important discussion today.It was found that accumulation of phlegm-wetness is one of major syndromes of EH.And mental stress is one of pathogenesis on incidence of EH through analyzing people's characteristic in working and life today.On the pathogenesis of EH,the scholars at home and abroad studies find that chronic inflammation plays an important role of incidence of EH,and hypertension is related to C-reactive protein and necrosis factor-alpha.Objective:To treat patients of EH with accumulation of phlegm-wetness with the therapeutic method of eliminating phlegm, tranquilizing and calming wind,then to observe effectiveness of EH and influence on biochemical parameters.Methods:Select 100 cases of EH according to the standard which the patients of EH are brought into.It is randomly divided into 2 groups which are given the same basic Western treatment.50 cases are in treatment group, and 50 cases in control group.The therapeutic method of eliminating phlegm,tranquilizing and calming wind(with recipe of eliminating phlegm, tranquilizing and calming wind)is given to the treatment group.The course of treatment of every group is 60 days.Grade of phlegm-wetness syndrome,blood pressure(BP),rhythm of the heart(HR),fat in blood,uric acid(UA),blood-glucose,fasting Insulin and C-reactive protein of every group are observed respectively before and after treatment,and then to compare.Results:1.After treatment,the grade and the curative effect of phlegm-wetness syndrome in the treatment group have been improved notably in comparison with those in the control group(the former P=0.000,the latter P=0.000).2.The BP in every group have been improved after treatment, and the BP in the treatment group has been improved more than that in the control group(SBP P=0.000,DBP P=0.049).the HR in the treatment group has been also improved notably than that in the control group(P=0.000).3.After treatment,the blood-glucose,fasting insulin and C-reactive protein in the treatment group have been improved notably in comparison with those in the control group(the former P=0.001,the latter two P=0.000).The UA,TC,LDL-C and HDL-C in the treatment group after treatment have been improved in comparison with those before treatment (all P=0.000),but haven't significant difference in statistics in comparison with the control group(P＞0.05).Because there is significant difference of TG between the two groups before treatment,there is no significance to contrast after treatment.Conclusion:On the basis of Western treatment,the therapeutic method of eliminating phlegm,tranquilizing and calming wind can improve the BP,HR and C-reactive protein more satisfactorily in the patients of EH with accumulation of phlegm-wetness.And it can probably improve the fat in blood and UA to a certain extent.