| Objective:To investigate the frequency of infections in different parts and their bacteria spectrum in elderly inpatients with type 2 diabetes mellitus,we attempted to evaluate the related risk factors in order to learn more about the infection characteristics of senior diabetic patients,thus we aimed to give a rational insight as well as provide an impetus for wider introduction of preventive approaches.Methods:To retrospectively analyze the clinical and laboratory data of 695 elderly inpatients with type 2 diabetes mellitus from Sir Run Run Shaw hospital of Zhejiang University during the year of 2004.1-2006.8..The inpatients with infection complications of senior type 2 diabetes were analyzed based on diagnostic criteria, using data from a retrospective study.A total of 291 were recruited.Collected data were analyzed by SPSS 11.5 software.Results:1.General data:There were 133 male and 158 female,with an average age of 71.75, average duration of disease 9.92 years,waist-to-hip ratio(WHR):0.91±0.78,body mass index(BMI):23.60±3.58kg/m~2,hemoglobin Alc(HbAlc):7.94±2.82%, fasting blood glucose(the first time after admission):9.65±5.40mmol/l, postprandial glucose(the first time after admission):14.50±5.55mmol/l,fasting blood glucose(the last time):6.96±2.21mmol/l,postprandial glucose(the last time): 10.33±2.94mmol/l.2.Infections in different parts:Among all parts of infections,the first four predominant parts were:respiratory system(137cases),urinary system(135cases), soft tissue(84cases),digestive system(41cases),accounted for32.16%,31.69%, 19.72%,9.62%respectively.There were statistical difference between male and female in constituent ratio of urinary system infection(P＜0.05).Most people with urinary system infection have no clinical symptoms.There were 32 cases in male and 85 cases in female have no clinical symptoms.3.Cases to be infected in different time:The cases of bacteria diagnosis for hospitalization regular examination were 186.The cases of bacteria diagnosis for people in hospital mainly because of infection were 105.111 cases have been infected in more than one parts at one time.4.Bacteria spectrum:Among all 126 cultivated bacteria,the cases for G+,G-,fungus, tubercle bacillus(TB)were35,43,47,1 respectively.The prevalence rate of conditioned pathogen in all cultivated bacteria was 82.54%(104 cases).The cases of bacteria diagnosis for hospitalization regular examination were:20 for G+,27 for G-, 37 for fungus,1 for tubercle bacillus(TB).The cases of bacteria diagnosis for people in hospital mainly because of infection were:15 for G+,16 for G-,10 for fungus. Respiratory system infection were characterized by significantly high lever of fungus,G-.Urinary system infection were characterized by G-,especially E coli.5.Risk factor analysis:Multivariate logistic regression model was used to identify independent risk factors for related infection complications.All data was stored and processed by using SPSS software version 11.5,95%CI＞1,p values≤0.05 were considered statistically significant.The risk factor related to urinary system infection was sex;related to respiratory system infection was fasting blood glucose;related to digestive system were macroangiopathy,blood pressure;related to soft tissue was blood fat.Conclusions:1.The prevalence rate of infection complications in elderly inpatients with type 2 diabetes mellitus were grimly high.The first four predominant infection parts were: respiratory system,urinary system,soft tissue,digestive system.2.There were statistical differences between male and female in the parts of infection. One of the feature is many old people infected in more than two parts at one time.3.The bacteria spectrum in different system is difference.4.Most urinary infected elderly inpatients with type 2 diabetes mellitus have no symptoms.It's reasonable that current therapy should cover as many risk factors like blood glucose,blood fat,blood pressure,macroangiopathy as possible. |
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