The Impact Of Self-monitoring Of Blood Glucose On Pregnancy Outcomes In Women With Gestational Diabetes Mellitus Received Pharmaceutical Care

Objective To study The impact of self-monitoring of blood glucose(SMBG)on pregnancy outcomes in women with gestational diabetes mellitus.Methods The study was conducted on 243 cases which are pregnant women with glucose metabolism disorders.According to the compliance of the patients,they divided into three groups.A group,72cases,checks blood glucose 7 times per day.B group,98 cases,checks 4 times per day.And C group,73 cases,checks less then 4 times per day or check randomly.Record all the information about those participators.Results There were no differences among the three group in women's age,body weight and body mass index(BMI)of pre-pregnant.The gestational weeks of pregnancy termination of C group(34.4±3.2w)is significantly earlier than A group (38.6±2.9w)and B group(38.1±2.1w),P＜0.05.The body weight and BMI before labor of C group(70.6±5.1kg,29.6±3.6kg/m~2)is statistical higher than A group(65.6±6.6kg,25.1±2.1kg/m2)and B group(66.1±7.8kg,26.8±4.4kg/m~2). There is no statistical differences of the incidence rate of pre-eclampsia, polyhydramnios,preterm labor,neonatal asphyxia,neonatal hypoglycemia and neonatal respiratory distress syndrome between A group and B group,except fetal distress(8.3%vs18.37%).Among the three groups,the incidence of complications is the highest in C group,pre-eclampsia(34.25%,9.72%,15.31%),fetal distress(36.97%,6.94%,18.37%),polyhydramnios(27.40%,5.56%,11.22%),preterm labor(38.36%,9.72%,20.41%),neonatal asphyxia(27.40%,6.94%,10.20%), neonatal hypoglycemia(41.10%,12.50%,20.41%)and neonatal respiratory distress syndrome(30.13%,4.17%,11.22)(P＜0.05).The incidence of premature rupture of memberane,fetal growth restriction,postpartum hemorrhage,fetal macrosomia and malformation has no statistical differences among three groups.There are 4 cases with fetal death and 10 cases with diabetic ketoacidosis.Conclusions(1)Checking blood glucose four times per day reduced the incidence of pre-eclampsia,polyhydramnios,preterm labor,neonatal asphyxia and so on.(2)The times of checking blood glucose related to the pregnancy outcomes.(3)Checking blood glucose seven times per day compared with four times per day only reduce the incidence of fetal distress.