Functional MR Imaging Of The Motor Cortex Lesion In Patients With Intracerebral Tumors

Objective To examine the functional areas of normal subjects and the patients with intrace-rebral tumor, and to judge whether the both functional areas of left and right hand are symmetrical in normal subjects, whether the activated functional areas in left hemisphere is larger than that of right hemisphere when the normal dextral use his right hand, and whether the normal sinistral's both activated functional areas are about equal; And to observe activation features of MI near to tumor and edema but without implication of MI functional regions , as well as that of MI where MI functional regions were implicated by tumor or edema. Methods 20 normal subjects and 24 patients with intracerebral tumor were performed with BOLD- fMRI technique. During each scan series, the patients were requested to perform repetitive finger - thumb opposition movement in the same period of active duration. All the scanning data were transformed to Functional work station and dealt with statistical method. Finally, we can get the brain functional map. Results For healthy volunteers, functional signal was not symmetrical . Most of volunteers showed a slightly stronger functional signal in left hemisphere than that of right. For the patients with motor cortex lesion, the results of fMRI studies demonstrated that the impact of lesion on motor cortex. Involved motor cortex displayed as decreased functional signal or migrated motor cortex. Conclusions fMRI can directly observe the location of functional areas, the relationship between lesion areas and adjacent functional areas and changes of functional regions, which shows an important instructing significance for resecting tumors near to motor cortex or motor cortex implicated. Postoperation can display the residual functional areas and provide objective evidence to evaluate the convalescence of brain functions.