308 Cases Of Pulmonary Embolism In Patients With Clinical And Epidemiological Research

Objective: To summarize and analyze the epidemiologic characters,clinical manifestations,accessory examination in pulmonary thromboemb-olism(PTE) in order to help the diagnosis and treatment of PTE.Materials and Methods: Retrospective analysis the clinical datas of 308 patients, who definitely diagnosed as PTE in the First Affiliated Hospital of Dalian Medical University from 2002 to 2006. Three hundred and eight patients were divided into three groups : acute massive PTE, acute submassive PTE and acute nonmassive PTE. Through analyzing personnel documents, the clinical manifestations, the laboratory examinations, the radiological examination and their prognosis, eachresearching element was carried on statistical analysis to provide proofs.Results: Male:184; female:124 the ratio:1.48:1. Age:15-88 years old,average age:60.45±14.04 years old.There existed marked difference among four age groups(p<0.05), so we concluded the older, the more morbidity. There existed marked difference in with or without basic diseases,so we concluded morbidity of PTE could be increased with basic disease. The successive morbidity among three types PTE is acute nonmassive PTE,acute massive PTE and acute submassive PTE(p<0.05). USG on legs vascular showed that single limb deep vein thrombus (DVT) is markedly more frequently than both legs(p<0.05),but there is not statistics significance between left and right leg. Conventional pulmonary arteriography showed that double pulmonary arteries filling defect is markedly more frequent than single one and right pulmonary artery filling defect was superior to that of left(p<0.05). Clinical manifestations of PTE were not unique. Symptoms in successive sequence are dyspnea,chest pain,fever,hemoptysis,syncope and angina pectoris.It could not be diagnosed as PTE only through blood gas analysis,ECG and X-ray,while CTPA was necessary to patients with high danger factors and suspected PTE. There failed to exist marked difference among three groups on therapeutic results.Conclusions: The morbidity of PTE is high and its clinical manifestations are complicated and various. There are some relationships among several symptoms. Suspected PTE patients should be timely,comprehensively and concerned inspected. Diagnosed PTE patients should be given anticogulations and thromoblysis therapy to improve survival rate. PTE is involved in many fields,therefore,it is very essential to improve doctor's standard diagnosis and treatment level.