The Study Of The Relationship Of Cervical Lymphonode Micrometastasis And Prognosis Of CN₀ Squamous Cell Carcinoma Of Tongue

Purpose: To investigate the relationship of the prognosis of the patients suffering tongue squamous cell carcinoma (SCC) with cervical lymph node occult metastasis(PN₁), micro metastasis (PN_m+), none metastasis (PN₀), in order to definite whether the patients with PN_m+ need postoperative radiotherapy as PN₁ .Methods: (1) Collect 54 cases of CN₀ tongue SCC treated in FuJian tumour hospital, ranged from Aug. 1993 to Dec. 2002. (2) All the paraffin block of PN₀ was restudied by immunohistochemistry stain (IHC) and in situ hybridization (ISH) with semi step section. (3) To add up the rate of death and the survival time. (4) All the data were analysesed with SPSS 10.0.Results: To the end of this study, all the patients with recurrence were dead. There is no significance in the ratio of death between the group PN₁ and PN_m+, and a significance between groupPN₁ and PN₀ as between the group PN m+1 and PN₀. There is no significance in survival time between group PN₁ and PN_m+,and a significance between the group PN₁ and PN₀ as between the group PN_m+ and PN₀.Conclusions: The prognosis of the patients with PN_m+.is equivalent with the patients with PN₁ . And they are poorer than the patients with PN₀. The patients with PN_m+ need postoperative adjuvant radiotherapy as the patients with PN₁ .