Cerebrovascular Diseases Directly Related Gene Mutation Research

Cerebrovascular diseases are major diseases which cause very extensive threats on human health and life quality. They lead to disability, high morbidity and mortality. There are complex interplay between the genetic factors and environmental factors affecting those diseases. There are two types of genetic factors: direct factors and indirect factors. The latter involve the genes that cause independent risk factors for cerebrovascular diseases like hypertension, hyperlipemia, hyperglycemia, hyperhomocysteinemia and so on. This article is mainly about the former, summarizes gene mutations which affect cerebrovascular diseases directly and independent from other diseases. Those genes are independent as risk factors for cerebrovascular diseases. They are divided by different mechanisms of function. Current researches about their relationships with cerebrovascular diseases are generally introduced in this article. Meanwhile, the articles in this review are screened by the standard of medical article classification. This review may provide significance to the gene therapy which brings new concepts and methods for individual medical care.