| Objective:To evaluate the difference of the detection rates and diameters of bronchial arteries (BA)between primary lung lancer group and normal control group,the relationship between diameter of BA and average diameter of mass,and also the difference of the detection rates and diameters between central lung cancer and peripheral lung cancer with multi-slice spiral CT imaging of bronchial artery.We also evaluate the display of BA using multi-slice spiral CT imaging of bronchial artery.Materials and methods:1.Multi-slice spiral CT imaging of bronchial artery was performed with a 16-slice spiral CT scanner(SIEMENS SOMATOM Sensation 16)in 225 patients.90～100mL contrast material(ultravist 300mgI/mL)was injected with high-pressure syringe at a flow rate of 3～3.5 mL/s.Delayed time was 20～23s or 26～28s in the elderly and patients with poor heart function.The Z scanning span was from about 3～4cm above the supra-clavicular fossa to the base of lung,scan time arrange from 7.4～12.7s. Routine scanning was started 40-45s after contrast material was injected.Thickness was 5mm and pitch was 0.9.Images of the first phase were reconstructed with thickness of 0.75 mm and intervals of 0.70 mm.Continuous axial images were used to recognize the origin and general course of BA.Post-processing technology such as MPR,MIP,VR and CPR was taken to display BA more clearly.64 patients confirmed as primary lung lancer by pathology were studied,in which 31 cases were central lung cancers(10 left,21 right)and 31 cases were peripheral lung cancers(17 left,16 right). 51 cases without any diseases in chest on CT were studies as normal control group.2.Recognition and measurement of BA:①number of BA in each side;the origin artery,original location of each BA and its relationship with main bronchus,numbers of cases showing left or right BA in each group②diameters of BA in normal control group and primary lung lancer group wew measured③average diameter of each tumor in primary lung lancer group④CT value of descending aorta was measured in tracheal bifurcation level.3.Statistical analysis:The data was analyzed by using the software of SPSS 15.0. P＜0.05 was taken to indicate statistical difference.Spearmen correlation analysis,chi-square test,t-test and Mann-Whitney U test were performed respectively to analyze the relationship between the diameter of BA and average diameters of tumor in primary lung cancer group,differences between arbitrary two groups in detection rate and diameter of BA,difference of CT values between groups with and without BA showing,difference of average tumor diameters between central lung cancer and peripheral lung cancer group.Results:1.Detection rates of BA was 82.61%(95/115 cases)in all cases,92.19%(59 /64cases)in lung cancer group and 70.59%(36/51 cases)in normal control group. 87(86.14%)right BA's original location were in the level of T5-6.66(65.35%)right BA origined from intercostal artery,34 from aorta and while 1 from right subclavian arter.77.78%(63 cases)left BA's original location were in the level of T5-6. 78(96.30%)BA origined from aorta,2 from intercostal artery and while 1 from arteria anonyma.2.The diameter of BA in lung cancer group had positive correlation to average tumor diameter.Detection rates of cancer groups were respectively 92.19%,100.00%,84.85%and normal control group 70.59%.Detection rates were different between lung cancer and control group,and also between central lung cancer and control group(P＜0.05).While there were no significant differences between peripheral lung cancer and control group,central lung cancer and peripheral lung cancer group(P＞0.05).The diameter of normal left BA was(0.0939±0.0269)cm and normal right BA was(0.1007±0.0241)cm in control group.There were significant differences in the diameters of BA between lung cancer and control group,central lung cancer and control group,peripheral lung cancer and control group.The diameter of BA in tumor side was(0.1776±0.0471)cm in central lung cancer and (0.1453±0.0375)cm in peripheral lung cancer group.There was significant difference in the diameters of BA of the two groups(P＜0.05).There was no significant difference in CT values of descending aorta between groups with and without BA showing.Conclusion:1.The detection rate is higher and diameter of BA is larger in lung cancer group than the ones in control group and the diameter of BA has positive correlation to average tumor diameter,which indicate that BA participates in the blood supply for lung cancer.The diameter of bronchial artery in central lung cancer was more larger than in peripheral lung cancer,which might suggest different types of blood supply between two groups.2.Multi-slice spiral CT imaging of bronchial arteriy is safe,fast and noninvasive technique.It could display BA by dearly and could to improve the achievement ratio in interventional therapy of lung cancer. |
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