Study On Monitoring Temperature And Tissue Lesion In HIFU Treatment Area Based On Ultrasonic Medical Image

High Intensity Focused Ultrasound (HIFU) as a new cancer treatment method has been received high attention recently. Because it is based on the principle that the thermal effect of high temperature result in tissue lesion, both the lesion evaluation and the thermometry of tissues are very important during the treatment. The traditional method for lesion evaluation is based on the experience of doctor, which is very easily leading to mistakes. Furthermore, the traditional thermometry depends on invasive methods, which bring much suffering to the patients, and sometimes it will cause tumor metastasis. Therefore, its application is largely limited.In this paper, the lesion evaluation and noninvasive thermometry are studied during the ultrasound treatment process. The relationship between B-mode ultrasonic image and the temperature of tissue are found. The main work we have done is as the following:1 A lot of researches have been done in the edge detection and edge enhancement, and an effective edge detection method using for B-mode image is put forward. Using the method can determine the edge of the Focal Region of HIFU automatically.2 We have analyzed the relationship between the gray characteristic of the B-mode image and the temperature of the tissue by a large number of experimental data. The results showed that the image gray-scale changes linearly with temperature changes.3 We have analyzed the relationship between gray characteristic of the B-mode image, fractal characteristics and the extent of tissue lesion. The results show that: it is very effective that using the average gray characteristic of the B-mode image and fractal characteristics evaluate the extent of tissue lesion.4 The frequency-domain analysis methods and neural network classification method are used in this paper. The results showed that the accuracy of the classification can reach 100%A large number of experimental researches have been done in this paper. The rules of the lesion evaluation and the thermometry of tissues are established. Although it is still difficult to achieve precise thermometry, these methods can accurately reflect the extent of the tissue lesion and the trend of the temperature change. In this paper, the research has important significance for the HIFU treatment, and the results have some reference value.