Artherosclerosis And The Changes Of Intracranial Arterial Hemodinamics Hem Odynam Ics In One Hundred And Fifty Samples With Primary Hypertension By Ultrasonic Inspection

Objective:To discuss the changes of carotid atherosclerosis and intracranial arterial hemodinamics in patients with essential hypertension.Methods:150 patients with essential hypertension according to the duration of disease in patients with essential hypertension were divided into three groups:Suffering from hypertension patients within five years(n=50),Suffering from hypertension patients within 5-15 years(n=50), Suffering from hypertension patients more than 15 years(n=50).In addition,50 healthy persons were selected as the control group.The patients were detected with color Doppler flow imaging (CDFI) and transcranial Doppler ultrasonography(TCD),and the results were analyzed retrospectively.Results:The results of TCD examination of intracranial arteries suggested that the end-diastolic blood velocity in three groups were significantly lower than that in the control group(P＜0.05);and both the pulsitive index and vascular resistance index were higher than the control group(P＜0.05).With the prevalence of extended life,Group sick between end-diastolic flow velocity gradually slow down(P＜0.05),Pulsatility index and resistance index gradually increased(P＜0.05).The detectable rates of increased carotid intima-media thickness(IMT) and plaques in the group of Suffering from hypertension patients within five years group were 30%(15/50) and 10%(5/50);the detectable rates of increased IMT and plaques in the group of Suffering from hypertension patients within 5-15 years group were 51.4%(26/50) and 19.7%(10/50);the detectable rates of increased IMT and plaques in the group of Suffering from hypertension patients more than 15 years group were 84.6%(42/50) and 35.8%(18/50);the control group were 9.5%(5/50) and 3.2%(2/50);Difference between the four groups were significantly(P＜0.05).Prevalence group peak velocity was significantly lower than the control group(P＜0.05),resistance index and flexibility index higher.Conclusion:Essential hypertension is an important risk factor for intracranial arteriosclerosis.CDFI combined with TCD may objectively evaluate the changes of hemodinamics of intracranial and extracranial arteries in patients with essential hypertension.