The Changes In The Syndrome Types Of TCM And The Correlation Between The Scores Of Cancer-related Fatigue And Quantifying TCM Synptoms In Patients With Primary Liver Cancer After Interventional Treatment

Objective:Study the changes in the syndrome types of TCM and the correlation between the scores of cancer-related fatigue and quantifying TCM symptoms in patients with primary liver cancer after interventional,in order to provide the evidence for syndrome differentiation and treatment of the patients with primary liver cancer after interventional.Materials and Methods:150 patients with primary liver cancer were subjected to TCM syndrome differentiation and grouped deficiency & excessive syndrome on day 3,day 7,day 14 and day21 after interventional therapies of primary liver,in order to be observed the changes of cases number Each of cm syndrome differentiation and grouped deficiency & excessive syndrome were scored by the method of cancer-related fatigue and symptom,then comparison the scores of cancer-related fatigue in syndrome combination and excessive & deficiency syndrome on day 3 afterinterventional.Results:1.The changes of symptoms type(1)On day 3 and day 7 after interventional,the proportion of two syndrome combination and three syndrome combination was more,but the proportion of three syndrome combination was decreased significantly on day 14 after interventional.The cases of single syndrome combination and two syndrome combination were gradually increased but three syndrome combination and four syndrome combination gradually decreased on day 3,day 7and day 14 after interventional.(2)On day 3,day 7and day 14 after interventional:the cases of qi stagnation and spleen deficiency type were gradually increased but the cases of blood stasis type,damp-heat type and yin deficiency type had less changed in single syndrome;The cases of spleen deficiency and qi stagnation type increased gradually but the cases of blood stasis+yin deficiency type and damp-heat+yin deficiency type decreased gradually in two syndrome combination;The cases of qi stagnation+blood stasis type had little changed in two syndrome combination.The cases of qi stagnation,spleen insufficiency with damp retention type decreased gradually in three syndrome combination;The cases of qi stagnation,blood stasis,spleen insufficiency with damp retention type decreased gradually in four syndrome combination.(3)The major trend was partial excessive syndrome(52.67%) on day 3 after interventional.The major trend is partial deficiency syndrome(42%) on day 7 after interventional.The major trend is deficiency-excessive syndrome(52.67%) on day 14 after interventional.(4)There were significant difference between the cases of partial deficiency syndrome on day 3 after interventional and the cases of partial deficiency syndrome on day 7 after interventional (p＜0.05).There were significant difference between the cases of partial excessive syndrome on day 7 after interventional and the cases of partial deficiency syndrome on day 14 after interventional(p＜0.05).There were significant difference in the cases of partial excessive syndrome on day 3 after interventional,the cases of deficiency-excessive syndrome on day 7 after interventional and the cases of deficiency-excessive syndrome on day 7 after interventional (p＜0.05).2.On day 3 after interventional(1)There were significant difference in the fatigue scores of five syndrome(p＞0.05) in single syndrome.Comparison in each syndrome:there were significant difference between qi stagnation type and spleen deficiency type,qi stagnation type and damp-heat type,qi stagnation type and yin deficiency type,blood stasis type and spleen deficiency type,blood stasis type and damp-heat type,blood stasis type and yin deficiency type,yin deficiency type and spleen deficiency type(p＜0.05),and there were no significant difference between qi stagnation type and blood stasis type,spleen deficiency type and damp-heat type,damp-heat type and yin deficiency type(p＞0.05).(2)If the combination of syndrome type was high,the level of symptom score was high and fatigue score was also high.There were both significant difference in the scores of symptom and fatigue in different combination of syndrome type.On the score of symptom and fatigue,there were all significant difference in single type-two type,single type- three type,single type- four type,two type-three type,two type- four type and three type-four type(p＜0.05).(3)On the scores of symptom,there were significant difference between partial dcficiency syndrome and partial excessive syndrome(p＞0.05);On the score of fatigue,there were significant difference between partial deficiency syndrome and partial excessive syndrome(p＜0.05).(4)There was positive correlation between the scores of quantifying TCM symptoms and cancer-related fatigue(r=0.572).Conclusions:1.This subject studied on the case observation of patients with primary liver cancer on day 3, day 7and day 14 after interventional,drawing the following conclusions:(1)Whether the combination of syndrome types or the concrete syndrome type is dynamic change.(2) The patients were grouped according to deficiency syndrome,excess syndrome and combination of deficiency and excess syndromes,who were the Changeing Trend of of partial excessive syndrome developing to combination of deficiency and excess syndromes developing to partial deficiency syndrome.2.By statistical results of this topic drawing the conclusion:we might alleviate symptoms through diagnosis and treatment and reduce scores of quantifying TCM symptoms to achieve the quantitative score lower cancer-related fatigue score of purpose,thereby enhancing the quality of life of patients.