| Objective : To investigate and compare the therapeutic effect between PLF and PLIF in the treatment of lumbar spondylolisthesis . Methods: Forty-eight patients with lumbar spondylolisthesis at grades 1 or grade 2 were treated with pedicle screw fixation and vertebrae fusion. Posterior lumbar fusion (PLF) was performed in 26 patients, and posterior lumbar interbody fusion (PLIF) was performed in 22 patients. The two groups were compared for clinical outcome (JOA), radiographic date (include: correction of slippage, disc space height, segmental lordosis and fusion rate) and complication rate. Results: In 1-5 year follow-up, the maintains of correction of slippage and disc height in PLIF group was better than those in PLF group (P<0. 05). The fusion rate and segmental lordos is in PLIF group was similar to PLF group (P>0. 05). No significant difference was found in terms of clinical outcome (JOA) and complication rate (P>0.05). The hardware failure rate was higher in PLF group than in PLIF group. Conclusion: Pedicle screw fixation with PLF or PLIF are both effective for spondylolisthesis at low grade. Pedicle screw fixation with PLIF confers superior mechanical strength in correction and maintain of spinal construct. Pedicle screw fixation with PLF has more loss of reduction and higher failure rate of hardware, but the clinical outcome is not influenced. |