The Clinical Research Of Yang-Qi Deficiency Syndrome Of Postinfaction Angina Pectoris From Biao And Ben Aspect

Objective: To evaluate the effects of Pei Tu Yi Yuan Tang on Yang-Qi deficiency syndrome of postinfarction angina pectoris and investigate the mechanism of it. Methods: Divided 60 myocardial infarction patients into two groups equally. A group named treatment group, B group named control group. We gave Pei Tu Yi Yuan Tang to A group besides western medicine for one month. For B group, we only used the same western medicine. When the treatment cycle was over, we observed the effects of Chinese materia medica. Indexes including frequency of angina pectoris attacks, dynamic electrocardiogram, blood-fat, the function of blood vessel endothelium, P-selectin, Doppler echocardiography and Nt-pro BNP of blood serum were measured respectively. Results: Pei Tu Yi Yuan Tang obviously decreased the anginal frequency and the expression of TC,TG,LDL-C,LP(a),ET-1,TXB2,P-selectin,Nt-pro BNP. It also increased the level of NO. In addition, this formula can improved the condition of Doppler echocardiography. Conclusion: Pei Tu Yi Yuan Tang has good effect to the patients of heart-stroke. Through this research, we think the mechanism including such aspects: improving the metabolic disorder of blood-fat, protecting the blood vessel endothelium, stabing the plaque, anti the activation of platelet, promoting thromboclasis, etc. In a word, this formula can protect the ventricular function and prevent myocardial infarction.