Analysis Of The Pathogenesis About 190 Cases Of The Pelvic Organ Prolapse

Object:Discussing the relationship of female pelvic organ prolapse(POP) correlating factors and the severity of this disease, and further more to understand whether there is relevance between stress urinary incontinence(SUI) and the severity of POP.Method:All of the 190 cases of female pelvic organ prolapse(POP) selected from inpatient hospital during January,1999 to December,2008, from the department of gynecology in the First Hospital of Jilin university are included in this study group.We gather and analyze the data of their age,height,body mass,their hometown(city or countryside) ,history of menstruation,frequency and method of delivery, history of abdominal surgery, chronical cough,chronical constipation,the state of urinary incontinence, other chronical disease (hypertension or/and diabetes ), and the type and severity of pelvic organ prolapse.Result: Grouping all the 190 cases according to their age we find that the incidence of moderate and severe POP has statistical difference ( P < 0.01).Comparing the relationship of BMI and severity of POP,we find statistical difference in different group.The difference in single-delivery group and multiple-deliveries group has statistical significance. Comparing the two groups of natural childbirth and Cesarean section, we find the incidence of severe POP has no statistical difference. And the difference between the two groups of city-patients and countryside-patients has no statistical significance. In the non-menostasis group the incedence of moderate POP is 50.0%(32 cases) and the incedence of severe POP is 4.7%(3 cases). In the menostasis group the incedence of moderate POP is 64.3%(81 cases) and the incedence of severe POP is 19.8%(25 cases). In other chronic disease group the incedence of moderate POP is 68.2%(28 cases) and the incedence of severe POP is 22.0%(9 cases), while in non-chronic disease group the incedence of moderate POP is 57.0%(85 cases) and the incedence of severe POP is 12.8%(19 cases).In the stress urinary incontinence(SUI) group the incedence of moderate POP is 62.3%(48 cases) and the incedence of severe POP is 22.1%(17 cases) ,while in the non-SUI group the incedence of moderate POP is 57.6%(65 cases) and the incedence of severe POP is 9.7%(11 cases). Three groups were significantly different (P <0.01) after statistically comparing. In the chronic cough group the incedence of moderate POP is 58.3%(7 cases) and the incedence of severe POP is 25.0%(3 cases),while in the non-chronic cough group the incedence of moderate POP is 59.6%(106 cases) and the incedence of severe POP is 14%(25 cases).This result shows us difference in the two groups has no statistical significance(P>0.05). In chronical constipation group the incedence of moderate POP is 50.0%(20 cases) and the incedence of severe POP is 20.0%(8 cases), while in non- chronical constipation group the incedence of moderate POP is 62.0%(93 cases) and the incedence of severe POP is 13.3%(20 cases).The result according to X2-test has no statistical significance. The same conclusion is got in the group of abdominal surgery history when the incedence of moderate POP is 60.0%(33 cases) and the incedence of severe POP is 10.9%(6 cases) but in the non- abdominal surgery history group the incedence of moderate POP is 59.3%(80 cases) and the incedence of severe POP is 16.3%(22 cases).Besides that comparison between SUI and female anterior vaginal prolapse shows us that there is no relevance between the severity of female anterior vaginal prolapse and SUI(P>0.05).Conclusion:The situation of SUI will aggravate according to the severity of pelvicocele but we need further research about the relation between SUI and female anterior vaginal prolapse.The severity of POP has close relationship with age and the situation of menstruation.Frequency of delivery should be an important reason for POP.When the frequency increases the incedence of POP increases it will aggravate.The same as with BMI.But we have no evidence to show difference between the patients in city or countryside.Further more, the severity of POP has relevance with other chronical disease (hypertension or/and diabetes ),but not for chronical cough,chronical constipation and history of abdominal surgery.