The The Application Of The Value Of MR Diffusion Weighted Imaging In Evaluating The Degree Of Hepatic Cirrhosis

【Objective】:To analyze the different levels of liver-hardening characteristics of the diffusion-weighted imaging and to the calculation of magnetic resonance diffusion-weighted imaging evaluation of the application of the value of the degree of liver cirrhosis,comparing the different degree of hardening of the liver apparent diffusion coefficient.【Methods】:According to history,clinical manifestations,laboratory examination and imaging examination,DWI were employed on 56 persons,including 20 normal people as a control group and 36 cirrhotic patients in accordance with their clinical manifestations and biochemical tests according to their Child-Puhg scoring system lesion group will be divided into A,B,C three groups(13 cases in ChildA level,12 cases in ChildA level and 11 cases in ChildC level).All selected lines are different b value diffusion-weighted imaging and calculation of ADC value,DWI were selected b value 0,100,200,400,600 s/mm~2.【Result】1.The value of ADC in Each goroup of cirrhosis were compared to the Sham group,at the b=100,200,400,600s/mm~2 respectively.We found that the value of ADC were decreased,and the degree was aggravated follow with the course of cirrhosis.And it had significant statistical differences among three different b value 200,400,600 s/mm~2(p＜0.01).To compare with each two groups,we found that it had significant statistical differences(p＜0.05) on the comparision of group B and Sham group,group C and Sham group,group A and C,when b=100s/mm~2.It had significant statistical differences(p＜0.05) on the comparision with group B and Sham group,group C and Sham group,group A and C,group B and C,when b=200s/mm~2.It had significant statistical differences(p＜0.05) on the comparision of group A and Sham group,group B and Sham group,group C and Sham group,group A and C,group B and C,when b=400s/mm~2.It had significant statistical differences(p＜0.05) on the comparision of each group,when b=600s/mm~2.2.It had medium inverse correlation between ADC values and the degree of cirrhosis.r= relation of b value and the degree of cirrhosis.The scope of the r was -0.722 to -0.930 when different four b value.The correlation between ADC values and the degree of cirrhosis was the best when b=600s/mm~2(r=0.930,p=0.00).【Conclusion】:1.DWI can evaluate the severity of hepatic cirrhosis.2.When b= 600s/mm~2,measured ADC values have the best correlation with the degree of the cirrhosis.