Comparison Of Clinical Efficacy Between Retroperitoneal Laparoscopy Nephroureterectomy And Open Nephroureterectomy For Treating The Transitional Cell Carcinoma Of Upper Urinary Tract

【Objective】To compare the clinical efficacy of retroperitoneal laparoscopy nephroureterectomy and open nephroureterectomy for treating the transitional cell carcinoma of upper urinary tract.【Methods】Thirty-six patients with transitional cell carcinoma of upper urinary tract underwent retroperitoneal laparoscopy nephroureterectomy and other twenty-nine patients underwent open nephroureterectomy synchronization. The operation time,blood loss amount,recovery time of intestine function,dosage of painkiller and hospital days were compared and analyzed. All the cases were followed up for 4-36 months and the survival rates,bladder carcinoma recurrence were recorded.【Results】All operations were completed successfully,no death occurred and there was no conversion to open surgery in group A. The mean operative time was (156±28)min in group A and (138±19) min in group B (P <0.05). The mean bleeding volume was (120±30) mL in group and (180±29) mL in group B (P <0.01). The recovery time of intestine function was (36.7±8.2)h in group A and (37.2±7.2) h in group B ( P >0. 05). The dosage of painkiller was (38.6±15.1)mg in group A and (50.9±19.7)mg in group B (P < 0.05).The hospital days in group A were (8.7±1.3)d and (9.2±1.8)d in group B (P > 0.05). The operation time in A group was similarly longer than that in the B group (P < 0. 05).The blood loss amount and dosage of painkiller in A group were shorter than those in B group (P < 0. 05). The recovery time of intestine function and hospital days were not significantly different in two groups(P > 0.05).The recurrence of bladder carcinoma was not significantly different in two groups during follow-up(P > 0.05).【Conclusions】Retroperitoneal laparoscopy nephroureterectomy has the advantages of less wound ,less blood loss ,less complications,complete specimen,rapid recovery and fitting the surgery principle of tumor radical treatment etc. It has become an ideal surgical technique for treating the transitional cell carcinoma of upper urinary tract.