San Zhisou Clinical Study Of Treatment Of Chronic Bronchitis

Objective:To observe and investigate the oral Zhisousan Powder western medicine(amoxicillin and ambroxol hydrochloride) in combination.The treatment of acute exacerbation of chronic bronchitis(cough cold pulmonary passage) the clinical efficacy. And to explore the role of Zhisousan mechanisms,in order to provide the scientific basis of clinical medicine.Methods:Chinese medicine and Western medicine meet the diagnostic criteria for acute exacerbation of chronic bronchitis, 60 cases of patients.Randomly divided into control group and treatment group,30 cases of the control group,30 cases of treatment group.Two groups in age,gender,disease duration, disease and other clinical information in general the difference was not statistically significant.Western medicine for the control group of oral amoxicillin and ambroxol hydrochloride,the treatment group to the above-mentioned Zhisou Powder and western medicine treatment,treatment for 14 days.Before and after treatment to observe the disease symptoms,signs,TCM Hou points, such as chest X-ray changes and clinical evaluation.All data SPSS16.0 system software used for statistical analysis. Measurement data((?)±s)that the use of t test and x~2test analysis.Results:1.The total effects of the two groups,treatment group,the total efficiency of 86.7%.The total efficiency of the control group 63.3%.The difference was significant(P<0.05). Efficacy of the treatment group than the control group.2.Auxiliary check chest X-ray determination,blood,and the determination of pulmonary function,compared to the situation in the two groups before treatment,P>0.05,no significant difference between the two groups.Routine determination of pulmonary function and the same group before and after treatment comparison, P<0.05,significant difference between the two groups.Comparing the two groups after treatment,P<0.05,two groups were significantly different efficacy of the treatment group than the control group.And chest X-ray determination,the same group before treatment and after treatment comparison,P>0.05,the two groups no significant differences in efficacy.Two groups after treatment comparison,P>0.05,no significant difference.3.The safety evaluation,not with the safety of drug-related abnormal indicators.Tip of the goods have better security. Conclusion:The addition and subtraction and Western Zhisousan(amoxicillin,ambroxol hydrochloride) in combination treatment of acute exacerbation of chronic bronchitis(cold passage of pulmonary type) significant efficacy.Has antitussive, expectorant and antiasthmatic effects.In the course of clinical trials,no drug-induced toxic side effects and adverse reactions.