Biological Properties Of Mica/apatite Glass-ceramics Coating On Titanium In Vitro

Objective: To evaluate biological properties of the mica/apatite glass-ceramics biomaterial coating on titanium used as a dental implant material by culture experiments in vitro.Method: The mica/apatite glass-ceramics biomaterial was coated on titanium by dipping, and was cultured in vitro with the cultivated osteoblasts of the mouse (MC3T3-E1),the biological properties affected with bioactive glass ceramics were observed and measured by light microscope,electron microscope,measure of alkaline phosphatase in supernant liquid and flow cytometer .Result: The osteoblasts grew well on the surface of the bioactive glass ceramics, and there were significant diferences of the ALP in supernant liquid and the proliferation index in the flow cytometry between the experimental and control groups (P<0.05)Conclusion: 1.Osteoblast growth in the experimental groups were better than the control groups'.2. Alkaline phosphatase content of the experimental groups more than the control groups'. 3. Biological properties of F5 groups were better than F8 groups.