Extrinsic Experimental Study On Rheum Officinale Baill Solution Antivirotic In Herpes Simplex Virus 2

Objective: To examine the effects of Rheum officinale Baill solution on the infection and replication of Herpes Simplex Virus 2, than to discuss the mechanism.Methods: Hela cell culture was used to detect the cytopathic suppression, Extracts the function by the different dosage Rheum officinale Baill solution in each stage of viral duplication cycle, by the viral half number of infections quantities (TCID₅₀), the cell pathological change (CPE), the MTT dyeing cell protection ratio (MTT) takes the appraisal target,to Judgment the efficacy of drugs.Than to appraise the antivirotic function in HSV-â…¡of Rheum officinale Baill solution. Results: The Rheum officinale Baill solution extracts to the Hela cell multiplication does not have the obvious function,Also is extremely low to the Hela cell toxicity,Has the direct deactivation function to the virus,May disturb the virus to the host cell adsorption,Also may effectively suppress the duplication of viral.Conclusions : Rheum officinale Baill solution has the remarkable suppression and the damaging effect to HSV-2.