| ObjectiveTo investigate the clinical features of facial dermatitis (FD) in Jinan and analyze the related pathogenic factors that could trigger and/or deteriorate the disease. With a view to define the common pathogenic factors of FD patients in Jinan and to provide a scientific foundation to future prevention and cure to the disease.Methods:One hundred and sixty-six cases of FD patients were selected and all of them were out patients of our department between October 2007 and October 2008.There were 138 cases of female (83.1%)and 28 cases of male patients (16.9%).A11 patients were interviewed with questionnaire to acquire detailed medical history , some of them were tested by patch test(PT) or skin prick test(SPT) for the information required. Use statistics software of spss 13.0 to sort out the data, chi-square test were used for count data and Kruskal rank-sum test were used if variance is not homogeneity. Take a=0.05 as the test standard, if P<0.05 means the difference has the statistic meaning or is significant correlation.Results:Among 166 samples of FD patients ,the ratio of male to female was 1: 4.93. The group of 20-40 year-old given the most Comparation of 59.6% . 89(53.6%)cases of patients were in spring and 15(9.0%) cases were in summer,and the cases of autumn and winter were 17(10.2%)and 45(27.1%). Contact dermatitis (CD) accounted for 30. 7% of FD. Among them , cosmetics accounted for 64. 7 % and topical drugs 9. 8 %.Hormone-dependent dermatitis (HDD)accounted for 21.1%.The most common primary disease of HDD is acne (25.7%) and CD (20.0%) .Followed by atopic dermatitis(AD)13.9%, seasonal contact dermatitis(SCD) 13.3%,seborrheic dermatitis(SD) 9.0%, dermatitis of unknown causes 8.4%, photosensitizing dermatitis 3.6%. 41 (24.7%) patients have constipation history and 14 (8.4%)with long-term insomnia.42(25.3%)patients have a history of drug allergy. Exacerbation factors among FD included chilly 57(34. 3 %), seafood 30 (18. 1 %), beef or mutton 24(14. 5 %), sunlight 41(24. 7 %), moist condition 20(12. 0 %), cold stimulate 14 (8.4%), dry condition 34(20.5 %).The top five common allergens of patch test(PT) were separately aromatic mixture (23.81%), nickel sulfate (19.05%), p-phenylenediamine (16.67%), thiomersal (14.29%), formaldehyde (11.90%); and the allergens with high positive rates in skin prick test (SPT) as follows: house dust mite, dust mites, animal hair I (hamster epithelium, dog epithelium, the rabbit epithelium, cat epithelium of guinea pig epithelial), tree-II (birch, beech, Quercus, Planetree), weeds.Conclusions:1. CD and HDD is the most common cause of FD.2. Acne and CD is the most common primary disease of HDD.3. Most of the FD patients are young and middle-aged female with a certain economic fundamentals and excessive attention to the facial skin.4. The unique topography and climatic conditions in Jinan results in the incidence of facial dermatitis in spring is significantly higher than other seasons.5. PT has a certain diagnostic significance for FD suspected of contact dermatitis.6. SPT is a kind of effective method for the patients of AD or with a physical of susceptibility... |
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