Ce Bai Sheng Fa Fang Treatment Male-pattern Alopecia Clinical Observation And Hair Scanning Electron Microscopy Combined With Energy Dispersion X-ray

Male-pattern Alopecia (MPA) is a gradualness alopecia of calvaria, temporal and forehead. Modern medical technique believe it is a hereditary disease depending on androgen, tradictional Chinese medicine believe that MPA is cause by liver-kidney asthenia, deficiency of essence and blood, damp heat and stasis of blood. ObjectiveDiscuss the clinical efficacy of the treatment on MPA in-differentiation of TCM base on "ce bai sheng fa fang". MethodThe research is prospective study, semi-random control trial was conducted.All cases came from out-Patients of the first hospital affiliated to Nanjing university of TCM, divided into two groups, all patients were male .50 patients in therapy group were treated by "ce bai sheng fa fang".30 patients in control group were treated by Finasteride. Improve of alopecia and condiction of hair-growing of two groups after 3months's treatment, decreases of oily-hair,head itching and quantity of scurf after 3months' treatment was observed and evaluated. And observed 120 cases of patients with MPA hair in the technology of energy dispersivex- ray microanalysis , and 50 cases with 50 cases of hair loss patients and normal human hair for comparison. ResultComparing age course of disease and degree of alopecia, there was no obvious difference between the groups, patients in both groups were well matched. But the curative of the treatment after 3 months ,the treatment decrease of oily-hair ,head itching and quantity of scurf of two groups ,treatment group was obviously better than that of the control group(P<0.05).The use of scanning electron microscopy combined with energy dispersion x-ray of patients with alopecia hair for trace analysis ,we found the structure of the hair of patients and partial hair element content of hair and compared with the normal degree of change are different. ConclusionThe research have proved that traditional Chinese medicine treat MPA effective and safe differentiations of TCM possess better improvement with main clinical adjoint symptoms of MPA ,can improve the life quality of MPA patients. Scanning electron microscopy combined with energy dispersion X-ray microanalysis at the micro-structure of hair, an objective quantitative and qualitative indicators, must have the significance of clinical research and development prospects.