| Objective: To study the correlations of the corneal aberrations among the age, diopter and the symmetry of the corneal aberrations between right and left eyes, to offer clinic data for diagnoses and treatments of ophthalm- opathy.Methods: 96 normal cases (192 eyes) including 54 males (108 eyes) and 42 females (84eyes) were recruited in the Refractive Center through the routine examinations and Topolyzer analysis. The average age was 25.8±4.0 years old (range 18 to 48 years old). The mean spherical diopter was -3.82±2.21D (range -2.59 to -10.74D), and the mean cylindrical diopter was -0.71±0.51D (range -0.05 to-2.44D). The relationship of corneal aberrations among age and diopter were analyzed, as well as the one between different eyes by using Zernike terms.Results: 1.For 6mm pupil the characteristics and distributions of the Zernike coefficients were described. 2.In the study the Z31, RMS3 of corneal aberrations increased with age. 3.The analysis of data showed spherical aberration correlated significantly with spherical diopter (r= -0.468, P<0.01) and coma aberration correlated with cylindrical diopter (r=-0.325, P<0.05). Coma aberration showed relationship with spherical diopter in high myopic group (r=-0.375, P<0.01). 4.Corneal Zernike terms were significantly sym- metric between right and left eyes.Conclusions: Coma in cornea increased with age. Spherical and coma aberrations had negative correlation respectively with spherical and cylind- rical diopter, and significant correlation was found between coma and sp- herical diopter in more than -6.00D group. There is a mirror symmetric character between left and right eyes. All the characteristics of the anterior surface of cornea provide theoretical bases for topography-guided custom corneal ablation, implantation of IOL, and diagnosis and treatment of keratoconus.
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