The Study Of The Relativity Between Wavefront Aberration And Diopter In Children With Ametropia, As Well As The Axial Length And The Corneal Curvature

Purpose：To study the relativity between wavefront aberration and diopter in children withametropia, as well as the relativity between wavefront aberration and axial lengthand corneal curvature respectively.(Wavefront aberration includes the RMS ofcoma aberration, spherical aberration,3-6aberration and high order aberration.)Methods：216subjects432eyes of children with ametropia were received the measurement,whose age were11.43±2.47years old. The Allegretto Waverfront Aberration Meterwas used for measuring the RMS of coma aberration, spherical aberration,3-6aberration and high order aberration after the pupils were dilated to6mm. The axiallengths were measured by A-scan. The corneal curvatures were taken by theTOPCON Computerized Subjective Refractometer. The SPSS17.0was applied toanalyze the the relativity between wavefront aberration and diopter(grouped by the SEdegree) in children with ametropia, as well as the relativity between wavefrontaberration and axial length and corneal curvature respectively.Result:1. The mean value of SE was-2.35±2.59D. The mean value of axial length was24.40±1.22mm.The mean value of H was42.63±1.34. The mean value of V was43.83±1.43. The mean value of AVE was43.24±1.35.2. The RMS of3-6aberration (purple diameter was6mm) were in a decreasingtrend from3aberration to6aberration.3. The correlation coefficient of the SE of ametropia in children and C12was0.100(p=0.039), which was a significant positive correlation. The correlationcoefficient of the SE of high myopia and RMS3was-0.387(p=0.046) and the correlation of the SE of high myopia and RMS6was-0.448(p=0.019), and thecorrelation of SE of high myopia and RMSh was-0.398(p=0.046), which weresignificant negative correlations. The SE of medium myopia and mild myopia had nosignificant correlation to the RMS of C7,C8,C12,3-6aberration and high orderaberration.The correlation coefficient of the SE of normal eyes and RMS3was0.447(p=0.042), which was a significant positive correlation. The correlationcoefficient of the SE of hyperopia and C12was0.389(p=0.013), and the correlationcoefficient of the SE of hyperopia and RMS4was0.470(p=0.002), which weresignificant positive correlations.4. The correlation coefficient of the axial length and the C12was-0.147(p=0.002),which was significant negative correlation. The C12was decreasing while the AL wasincreasing.5. The correlation coefficient of the corneal curvature H and the C12was0.159(p=0.001), and the correlation coefficient of the AVE and C12was0.120(p=0.013). The corneal curvature H, the AVE and C12were in significantpositive correlation. The C12was increasing while the corneal curvature H and theAVE was increasing.Conelusion:The axial length was increasing while the degree of myopia children wasincreasing, but the SA was decreasing. It might be an adaptive mechanism that theincreasing length of axial can decrease the SA. Therefore the SA played an importantrole in the progress of myopia. The SA was increasing while the corneal curvature Hand AVE was increasing. There was a significant negative correlation between the SEof high myopia and RMS3,RMS6,RMSh. There was a significant positive correlationbetween the SE of normal eyes and RMS3,as well as the correlation between the SEof hyperopia and C12,RMS4. The SE of medium myopia and mild myopia had nosignificant correlation to the RMS of C7,C8,C12,3-6aberration and high orderaberration.