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The Prevalence Of Metabolic Syndrome In People Of Dalian Zhangzidao And The Relationship Between Metabolic Syndrome And Blood Glucose

Posted on:2010-11-28Degree:MasterType:Thesis
Country:ChinaCandidate:N ZhangFull Text:PDF
GTID:2144360278953051Subject:Internal Medicine
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Objectives:Inorder to understand the epidemic condition of metabolic syndrome (MS) and study the relationship between MS and blood glucose.Methods:We selected 907 subjects who lived in Dalian Zhangzidao and the age above 18 years (413 men and 494 women,mean age 44.06±15.22years).The data of the subjects include body height,body weight,waistline,hip circumference,blood pressure,triglyceride(TG),fasting plasma glucose (FBG),2-hour postprandial blood glucose(2hPG),high-density lipoprotein cholesterol(HDL-C) and we also calculated body mass index(BMI).All study subjects were classified into 4 groups according to the age(10 years old as a interval)and calculated the prevalence of MS and its components. All study subjects were classified into 7 groups according to the FBG(0.5mmol/L as a interval),classified into 9 groups according to the 2hPG(0.5mmol/L as a interval)and calculated the prevalence of MS and its components,then compared the prevalence of MS and its components among different blood glucose levels.Results:1,The prevalence of MS in Dalian Zhangzidao is 21.3%,and the prevalences of its components including hypertension,hypertriglyceridema, high blood glucose,hypohigh-density lipoprotein cholesterol,overweight and/or obesity are 44.5%,21.8%,47.6%,4.2% and 52.7%.2,As the age rising ,the prevalence of MS in Dalian zhangzidao is increasing.The differences among 4 age groups has statistical significance (P< 0.05) .The prevalence of MS is obvious increasing after 45 years old.The prevalences in each group are 8.8%,24.6%,54.1%,52.7% and the OR value are 3.39(95%CI:1.90-4.13),5.38(95%CI:3.35-8.67),11.61(95%CI:6.66-20.33)respectively.3,The prevalence of MS in Dalian zhangzidao has a sexual difference.Below 45 years old,the prevalence in male is higer than female and the the difference has statistical significance(χ2=4.15,P<0.05). Above 65 years,the prevalence in female is higer than male and the difference has statistical significance(χ2=4.17,P<0.05).The prevalence of hypertension in male is higer than female and the difference has statistical significance (χ2=13.96,P<0.01).4,The datas including age,waistline,hip circumference,systolic pressure,diastolic pressure,BMI and TG have differences among different FBG and 2hPG groups(P<0.01). As the rising of FBG and 2hPG,the mean values of the datas are increasing.5,When the FBG and 2hPG increase,the prevalences of MS and its components including hypertension,hypertrihltceride,overweight or/and obesity also increase.The cutoff point of FBG to differentiate the risk of MS is 5.6mmol/L and 2hPG is between 7.4-9.5mmol/L.Conclusion:1,The prevalence of MS in Dalian Zhangzidao is 21.3% which is higher than that of adult in large and middle cities in China. The prevalence has a sexual difference.The age below 45 years old is the dangerous age to MS.The prevalence of hypertension in male is higer than female and the difference has statistical significance2,When the FBG and 2hPG increase,the prevalences of MS and its components also increase.The cutoff point of FBG to differentiate the risk of MS and its components is 5.6mmol/L and the cutoff value of 2hPG is between 7.4-9.5mmol/L.Compare with the FBG,2hPG has a larger variability of predicting MS and its components.
Keywords/Search Tags:metabolic syndrome (MS), fasting plasma glucose(FBG), 2-hour postprandial blood glucose (2hPG), prevalenc
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