The Clinical Characteristics And Prognosis Analysis Of Intracerebral Hemorrhage

[Objective]To analyze the clinical history of patients in Shandong Provincial Hospital affiliated to Shandong University during 2005-2008,so as to discuss the risk factor of prognosis,epidemiology,clinical characteristics in Shandong area,and introduce the holistic and individual therapy on the basis of clinical stage.[Method]1.According to the clinical history of 460 patients in our hospital,to compare the different courses with age and sex,characteristics,clinical symptoms,physical signs,laboratory examinations,complications and prognosis.2.We assigned to four age groups:young group(≤44),Middle-Age group(45-49), older age-group(60-74) and oldest age-group(≥75).Course stage was divided into three:acute stage(within 3 days),subacute stage(4-14days) and convalescence stage(exceed 14 days).3.Statistical analysis and graph manufacture were carried out with spss15 statistics software,measurement data were demonstrated by((?)±S),to transform into classified variable when necessary;numeration data were demonstrated by ratio or constituent ratio;to contrast the mean of two groups with t test;to contrast multi-group data with analysis of variance;to contrast numeration data with chi square test,statistical significance criterion wasα=0.05.【Results】1.Among 460 patients,male is 293 and female is 167,the male female ratio(M-F) is 1.75:1;M-F is 1.75:1 in the group of Hypertensive Intracerebral Hemorrhage (HICH),while M-F is 1.78:1 in the group of non- Hypertensive Intracerebral Hemorrhage(non-HICH).The age is 58.18±13.02 in the HICH and 60.06±18.55 in the non-HICH,the constituent ratio of two groups is variability(P＜0.05).2.In the HICH group,M-F is 12.75:1 among young group,1.68:1 among Middle-Age group,1.04:1 among older age-group and 1.63:1 among the oldest age-group;in the non-HICH group,M-F is 1.4:1 among young group,2.71:1 among Middle-Age group,1.17:1 among older age-group and 2.28:1 among oldest age-group.3.Season morbility:92 in spring(20.00%),73 in summer(15.87%),137 in autumn (29.78%),158 in winter(34.35%),Nonparameter test demonstrated significant difference of season morbility.4.The onset of ICH in the condition of sleep or resting state was 66(14.35%),394 (85.65%) were began in the condition of common physical work,exertion or excitement.5.The patients who have history of hypertensive disease or cerebral apoplexy were 77(21.57%),female is 23 while male is 54.6.127 patients have the history of smoking,include 2 female patients;122 patients have the history of alcohol abuse include 3 female patients.The male who have history of smoking or alcohol abuse is more than female.7.In the different courses of ICH,the comparison of heterophil granulocyte and its percentage,platelet,blood glucose,four items of the natural bleeding and blood coagulation,low density lipoprotein,blood biochemistry and urea nitrogen have significant difference(P＜0.05).8.Single-factor analysis indicated that blood pressure after illness,complications, haemorrhage broken into cerebral ventricle have significant difference to prognosis(P＜0.05).9.Stepwise regression analysis indicated that age,volume of blood,conscious disturbance after illness,complications and fervescence were major factor relate to prognosis.【Conclusions】Sex difference is obvious in the intracerebral hemorrhage patients,male is more than female.High blood pressure is the most major risk factor,the morbility in young male is far outclass young female.Age,volume of blood,conscious disturbance after illness,complications and fervescence were major factor related to prognosis.