Study Of Carotid Artery Remodeling By Quantitative Tissue Velocity Image In Essential Hypertension Patients With Different Patterns Of Left Ventricular Geometric Models

Objective:This study aims to probe into the carotid remodeling ultrasonic manifestation in Essential Hypertension Patients with different patterns by way of the quantitative tissue velocity imaging(QTVI) technology,so as to provide valuable information for clinical diagnosis and treatment in EH as well as for the prediction of risky factors of its complications in cardiovascular and cerebrovascular disease.Methods: Control group:35 healthy volunteers are selected by the inquiry,body check-up,ECG and chest X-ray examination precluding abnormal hearts and lungs,of which 18 are males,17 females,averaging 56.26±14.78 years old.Hypertension Group:Essential hypertension 99 cases are chosen according to the 1999 WHO hypertension diagnostic criteria,of which the normal pattern of left ventricular(LVN) Group made up 32 cases,M 17,F 15, averageing 59.59±13.49 years old;left ventricular remodeling(LVR) Group 32 cases,M 17,F 15,averaging 57.03±14.55 years old;left ventricular hypertrophic(LVH) group 35 cases,M 17,F 18,averaginh 60.51±12.57 years old.PHILIPS IE33 color Doppler ultrasound diagnostic apparatus has been employed as instrument with probe L11-3 and probe S5-1(frequency of 4.0～8.0MHz and 1.9～3.8MHz respectively) to test the parameters of Tissue Doppler,two-dimensional and hemodynamic parameters of the carotid artery.Results 1.Carotid artery quantitative tissue Doppler test results:①Vimax, Aci were significantly reduced compared with the control group with statistical significance(P＜0.05);and The Vimax,Aci values of the LVN group,LVR group,LVH group are followed by reduction of its inter-group comparison,showing statistical significance(P＜0.05).②Ati,Dti are significantly shortened compared with the control group with statistical significance(P＜0.05).And the Ati,Dti decreased successively among the LVN Group,LVR group and LVH group with statistical significance(P＜0.05). 2.The two-dimensional carotid artery ultrasound test results:①LVR group and LVH group Internal Media Thickness(IMT) values have increased compared with the control group with statistical significance(P＜0.05),but the IMT of the LVN group shows no significant difference with the control group(P＞0.05).Difference between LVN group and control group is not statistically significant.②LVH group Ds and Dd have increased,and the contrast with the control group was significant(P＜0.05).③βvalues of hypertension group has increased,compared with the control group with statistical significance(P＜0.05).④The DC of hypertension group dereases compared with the control group with statistical significance(P＜0.05).3.Single factor correlation analysis has showed that IMT in patients with essential hypertension is positively correlated with LVMI,and in the impact of the multi-factor regression analysis of IMT,Vimax enters the regression equation first,followed by LVMI.Conclusion:1.Quantitative tissue velocity imaging(QTVI) technology can evaluate the remodeling characteristics of carotid artery in Essential Hypertension Patients with Different Patterns of Left Ventricular Geometric Models.2. The parameters reflecting left ventricular remodeling and carotid artery remodeling parameters have good correlation,and the occurance of carotid artery remodeling is earlier than that of left ventricular remodeling.And,therefore,QTVI,as early and sensitive indicator in detecting hypertension carotid artery remodeling provides valuable information for clinical diagnosis and treatment of hypertension,as well as the prediction of the risky factors of its complications:the cardiovascular and cerebrovascular disease.