Analysis Of Jugular Vein Oxygen Saturation And Cerebral Extraction Of Oxygen In Patients With Severe Trauma Brain Injury

Objective To obverse changes of jugular vein oxygen saturation (SjvO₂) and cerebral extraction of oxygen (CEO₂) in patients with severe trauma brain injury, and to evaluate the relationship of outcome to jugular vein oxygen saturation.Method 24 patients with acute severe trauma brain injury were studied; meanwhile 10 patients with acute mild to moderate trauma brain injury were used as the control. By using a technique of jugular catheterization and blood sampling everyday, the changes in SjvO₂ and CEO₂ were observed and were compared. Furthermore, the relationship of prognosis to SjvO₂ was analyzed.Results For patients with severe trauma brain injury, on the first day post-injury, SjO₂ decreased, CEO₂ increased; on the second-fourth day, SjO₂ increased, CEO₂ decreased, as compared with mild to moderate patients .Those were difference on statistics. But on the fifth day SjO₂ and CEO₂ of those were not difference. SjvO₂ in patients with severe trauma brain injury was correlated with prognosis, SjvO₂<50% or SjvO₂>75% were associated with poor outcome.Conclusions When the brain is severely injured, there is cerebral hypoxia or ischemia during the first 24 hours, and cerebral hyperemia in the following second-fourth days. Changes of SjvO₂ and CEO₂ could reflect indirectly status of cerebral metabolism of oxygen in patients with severe trauma brain injury, SjvO₂ have the value of therapy and prognosis in patients with severe trauma brain injury.