| Along with the rapid development of global economy, population and lifestyle changes, the prevalence of diabetes also increases rapidly. At present, all sorts of diabetes TongZheng acidosis, acute (diabetes TongZheng not high permeability diabetes coma, etc.), chronic infection (large vessels and nerves, eye, capillaries, diabetic foot) has been widely concerned complications.For the first time since 1948 Albright report long-term poor blood glucose control diabetes can occur with osteoporosis, diabetes and osteoporosis relation also cause the attention of people. Osteoporosis is various causes of metabolic bone disease, is a kind of important alzheimer's disease. Osteoporosis is a developed country, the most important public health problem is one of the developing countries and a prominent problem. It is the 21st century with diabetes with the main diseases, serious impact on human health. China has become an aging society, type 2 diabetes and osteoporosis, both for the elderly, the study of the relationship between diabetes and osteoporosis for preventing senile disease, improve the level of health is of great significance.Diabetes is systemic chronic diseases, the metabolic endocrinology for insulin physiological pathology absolute or relative shortage, mainly for sugar, protein, fat, but three material metabolic disorder is associated with bone metabolism and diabetes, patients with diabetes because of the abnormal insulin decrease and function abate, the reduction in the number of osteoblasts, activity, make the formation, thus reduce [1] different degree of bone loss. Osteoporosis is bone strength and fracture risk increases as the characteristics of the skeletal system disease. Primary osteoporosis is divided into postmenopausal osteoporosis and senile osteoporosis. Secondary osteoporosis is because diabetes endocrine disorders and other diseases or drugs and other factors that trigger osteoporosis. For diabetes mellitus and the heart, blood vessels and nerves, chronic kidney disease etc for clinical research institute has been confirmed, and osteoporosis belong to many causes disease, osteoporosis T2DM concurrent factors affected the mechanism and related factors affecting the complex, gender, age, weight, genetic, environmental, lifestyle, hormone and local cell factors of osteoporosis is to play a role, at the same time and adjust osseous metabolism and bone mineral metabolism. Precisely because of the diabetic osteoporosis pathogenesis is complex, so the incidence of diabetes and osteoporosis is increasing, the serious harm to human health.Currently most studies suggest that patients with type 1 diabetes, metabolic abnormalities and existing bone osteoporosis merger bone loss and [8], and type 2 diabetes bone changes affected by various factors and changes to differ, low [9], normal or increase [10]. Bone mineral metabolism is BMD quantitative index of the bone, BMD measuring provides an early diagnosis of osteoporosis and effective sensitive means of inspection. Currently the world recognized diagnosis of osteoporosis is the gold standard dual-energy X-ray absorption method to detect bone [11]. This study explores the diabetes incidence of bone and osteoporosis. Diabetes is a chronic blood glucose levels increased with the metabolic disease characterized, mainly for sugar, protein, fat, but three material metabolic disorder, many studies have demonstrated that also involves salt and water electrolyte, all kinds of trace elements and bone mineral metabolic abnormalities. The study of diabetic patients bone mineral density change and related factors analysis found that people with type 2 diabetes compared with age group bone mineral density, osteoporosis, differences were not significant morbidity. Diabetes for chronic endocrine metabolic diseases for insulin physiological pathology its absolute or relative deficiency, and insulin in bone metabolism process is directly involved in effect, insulin can promote PTH, 1, 25 (OH) 2D3, insulin-like growth factor (IGF - 1) on the role, make the OB sign up, their actiity increased collagen synthesis and matured, thereby [17] density increases. So of diabetic patients should be strictly control blood sugar, maintain good weight, regular bone densitometry.the, early detection and prevention osteoporosis, reduce the risk of fracture. This study adopts dual-energy X-ray absorptiometry (dexa) fifty-two patients with type 2 diabetes (diabetes) and 60 healthy check-up (control group) were lumbar 2 ~ 4 and left proximal femoral BMD, patients with diabetes were observed and bone density, biochemical, metabolic endocrinology related indexes.Results:No matter male and female compared with the normal control group T2DM, though, but reduce BMD no statistically significant differences. T2DM group whether male or female and age were compared to the prealence of OP, but just above healthy controls, with no significant difference with the growth of the age, OP the prealence of also increased year by year. In diabetics, two group of bone and reduce blood glucose and bone of normal insulin levels were higher than normal, but no statistically significant difference between each group (P>0.05). In diabetics, the lower level of bone HbA1c than the normal group, bone statistically significant (P<0.01). In diabetics, the lower level of PTH bone, CT, and healthy controls reduced levels of normal bone and diabetes compared are statistically significant difference (P<0.05), diabetes and CT PTH of normal bone health level and the difference was not statistically significant (P > 0.05). Diabetes bone and reduce the blood of normal bone blood calcium, phosphorus, compared with healthy controls ALP level was not statistically significant (P>0.05). Conclusions:1. patients with type 2 diabetes and femoral BMD and lumbar spine of osteoporosis and normal rates of similar.2. age, long-term history of diabetes, low for body-mass index, female duration ofmenopause for type 2 diabetes mellitus risk factors for osteoporosis.3.type 2 diabetic patients with bone change parathyroid hormone (PTH), calcitonin (CT) calcium adjusting hormonal changes.4. for patients with type 2 diabetes should be strictly control blood sugar, regular bone and bone metabolism and biochemical indicators testing, early detection and prevention osteoporosis, reduce the risk of fracture afterwards.
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