| Objective:To analyze histiocytic necrotizing lymphadenitis (HNL),including the denominate, epidemiology, etiology, clinical manifestation, auxiliary examination, pathology, diagnosis and differential diagnosis, treatment and prognosis.Methods:Combining the repesentative case of histiocytic necrotizing lymphadenitis (HNL), search former literatures and analyze this disease.Conclusions:Histiocytic necrotizing lymphadenitis (HNL) is called necrotizing lymphadenitis, virus lymphadenitis, sub-acute lymphadenitis or Kikuchi Fujimoto Disease, which was first reported and denominated by Japanese Kikuchi and Fujimoto in 1972. It is benign, self-control, systematic disease which involves lymph nodes and often happens on young women in the east without clear etiology. Its manifest shows fever, lymphadenectasis, rash and so on. HNL is easily mistakenly treated for absence of specificity, low incidence rate, unfamiliarity with this disease and difficulty identification with other lymph nodes diseases. |