The Short-term Influence Of Panretinal Photocoagulation On Macular Retinal Thickness And Volume In Diabetic Retinopathy

To investigate the short-term influence of panretinal photocoagulation(PRP) on macular retinal thickness and volume in diabetic retinopathy(DR).MethodsSeventeen patients(30 eyes) with diabetic retinopathy at stage III-IV were treated by changing the sequence of PRP from downside quadrant, nasal quadrant, upside quadrant and then temporal quadrant The PRP was performed one quadrant once a week, and finished in four weeks. Optic coherence tomography examination was performed before, the 1st week, the 2nd week, the 3rd week after the first laser photocoagulation, the 1st mouth and the 3rd mouth after the PRP finished.ResultAt the 1st week, the 2nd week, the 3rd week after the first laser photocoagulation, the 1st mouth and the 3rd mouth after the PRP finished, significant increasing of macular thickness and volume was observed and the most extent of macular retinal thickness increasing was found in the 1st mouth, especially in the fovea macula Al,and also A2 and A5 in the inner,A8 and A9 in the outer. At 3 mouths after first laser photocoagulation, the retinal thickness was decreasing.ConclusionSignificant increasing of macular retinal thickness and volume in DR after PRP, especially in fovea macula and temporal quadrant, reveals progressed macular edema by PRP.