Of Smoking On Bronchial Asthma Inhaled Glucocorticoid Treatment Effect

PrefaceBronchial asthma (bronchial asthma, referred to as asthma) are from a variety of cells (such as eosinophils, mast cells, T cells, neutrophils, airway epithelial cells, etc.) and cellular components involved in chronic inflammatory airway diseases. At present the treatment of glucocorticoid bronchial asthma the most effective anti-inflammatory drugs, which can effectively suppress airway inflammation, to improve the patient's clinical symptoms, lung function and airway hyper-responsiveness. However, these studies have generally aimed at non-smoking groups, thus bringing up to 1/3 of smoking in patients with asthma excluded from the scope of the study. The incidence of smoking and asthma have a certain relationship with the non-smoking asthmatic patients compared to smoking are often symptoms of more serious asthma, lung function declined faster, make the incidence of asthma, hospitalization and death rates rise. It can be said of smoking on airway inflammation in patients with asthma impact and smoking on the adrenal cortex in patients with asthma responsive to hormone therapy have been ignored. This study focuses on effects of smoking on bronchial asthma inhaled glucocorticoid treatment effectObjectiveObjective To observe the effects of smoking on inhaled corticosteroid in patients with bronchial asthma therapeutic effect.MethodsMethods for non-smokers (20 cases) and smoking (21 cases) and bronchial asthma were treated with Seretide (salmeterol and fluticasone propionate inhalation powder) each time a suction (50 micro-Kashagan America Quintero and 250 micrograms of acid fluticasone),2 times a day. Continuous observation in February, respectively, in the treatment of 1 week,2 weeks,1 month and 2 months subsequent visit, records day and night after the treatment of asthma symptom scores, to determine clinical efficacy.ResultsThe results of treatment in patients with non-smoking group is better than smokingpatients (P<0.05).ConclusionsSmoking significantly decreased in patients with bronchial asthma, inhaled corticosteroid efficacy in patients with bronchial asthma should actively stop smoking in order to obtain a better efficacy.