The High-risk Factors For Bronchopulmonary Dysplasia In Premature Infants With Mechanical Ventilation

ObjectiveTo study the high-risk factors for bronchopulmonary dysplasia(BPD) in premature infants with mechanical ventilation.MethodsFrom January 2008 to Decemeber 2009 one hundred and ninety-six very low birth weight infants with gestational age less than 32 weeks in our NICU were enrolled in the study. Sixty-one cases had the histories of mechanical ventilation. Twenty-one with BPD were compared to forty ones without BPD in the clinical materials.ResultsThe gestational age and birth weight of BPD group were lower than those without BPD,and the rates of premature rupture of fetal mambranes and complicated RDS,postnatal infection,PDA,with long time intravenous nutrition in BPD group were highter than those of the control(p<0.05);gender,asphyxia history,the use of PS,PEEP,MAP have not been found more different between the two groups(p>0.05);PIP,the time of mechanical ventilation and oxygen administration were longer in BPD group(p<0.05).ConclusionShorting the time of mechanical ventilation and oxygen administration, Preventing RDS and the recurrent infection play very important role in preventing the bronchopulmonary dysplasia(BPD).