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3.0T MR Image Signs Of Local Infiltration In Rectal Cancer With Its Pathological T Staging: A Comparison Study

Posted on:2011-01-19Degree:MasterType:Thesis
Country:ChinaCandidate:J L WangFull Text:PDF
GTID:2144360305458745Subject:Medical imaging and nuclear medicine
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ObjectiveUsing 3.0T MR of primary tumor local infiltrating rectal carcinoma preoperatively degree evaluation, Mainly discusses the local invasion of rectal cancer signs and rectal cancer MRI diameter. With pathology results as the gold standard, The results In the primary discussion 3.0 T MR tumor local infiltrating rectal cancer patients preoperative evaluation of degree.Materials and MethodsThe tumor surgery for collecting since July 2009-2010 between January confirmed by pathology after the sixty-two cases of rectal cancer cases, preoperative magnetic resonance imaging, magnetic resonance imaging to accept on intestinal preparation. Check for 20 minutes before the patient 20mg 654-2, restrain bowel movement (with heart disease, glaucoma and prostate increase the living except),40 degrees Celsius (200-the warm 450ml) irrigation anus.All of the patients in MR examination after 1-16 days (mean interval for 5 days) underwent surgical treatment, operation according to the total mesorectal straight mesenteric resection (excision, TME principles). Using 3.0T MR to analyze local infiltrating signs of rectal cancer staging diagnosis, classification, make,And postoperative pathological and histological tumor T stage comparison,By histopathological results as the gold standard, Use of SPSS statistical analysis software 13.0 calculated in the evaluation of tumor 3.0T MR local infiltrating degree of overall accuracy and sensitivity and accuracy of the stage, specificity, positie predictie, negative predictive value. Spearman and correlation analysis of local infiltrating signs and intestinal tumor size and the related degree pathological results. ResultsSixty-two cases of rectal cancer patients, including 36 male,26 female, age 35~83 years old, age 62. Upper section 12 cases rectal cancer,28 cases of rectal cancer in the middle,under section 22 cases of rectal cancer.18 routine abdominal perineal joint resection,42 regular rectumbefore,3 routine palliative resection. Well-differentiated adenocarcinomas,10 cases were differentiated adenocarcinoma in 40 cases, low differentiated adenocarcinoma in 6 cases, mucous adenocarcinoma 6 cases. Final pathologic stage shows or T2 stage 14 cases of 27 patients, T3, and T4 21 cases. MRI correct T stage 48 cases, error 14 cases.the overall diagnostic accuracy of T staging was 77.4%, MRI diagnostic accuracy of≤T2-T4 staging was 88.71%,77.42%and 88.71%, respectively. The relationship between the MR signs of local invasion and the pathological T staging was strong positive (rs=0.725,P<0.001). The relationship between circumference invasion of rectal cancer and the pathological T staging was ordinarily positive (rs=0.699, P<0.001). With the infringed the increase of intestinal weeks, pathology diameter increased gradually T stage. Pathological acuities T2 stage cases only 7%(1/14) bowel tumor invasion than 1/2 diameter weeks, Pathological T3 cases infringing bowel cancer than 1/2 diameter weeks of rounded (20/27), Have 95.2% (20/21) pathology T4 cases infringing bowel cancer than 1/2 diameter weeks.Conclusion3.0T MR can accurately for rectal cancer preoperative evaluation of local infiltrating degree. Correct identification of MR signs and the evaluation of the extent of the circumference invasions of rectal cancer are conductive to the T staging of rectal cancer.3.0T MRI with a phased -array coil is an accurate imaging tool to evaluate T staging of rectal carcinoma. On the important muscle tissue, Such as anal muscle, puborectalis sling, and anus sphincter have invasioned and degree evaluation can correctly.This technique is helpful in preoperatively selecting the patients who will perform chemotherapy and radiotherapy and planning the surgery programme to make sure a complete removal of the lateral spread of the tumor and reduce local recurrence rates.
Keywords/Search Tags:Rectal neoplasms, Magnetic resonance imaging, Neoplasm staging
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