| Objective:To provide references for drawing and outlining the real target volume by means of applying x-ray stimulator to observe respiratory motion and by exploring the influence factors of mass displacement of lung cancer solid tumor.Methods:Based on X-ray stimulator, using fluoroscopy, we observed the movement of tumors. Viewletcam software recorded the video process, and then it was decomposed into a sequence of images. applying Photoshop software, we processed the sequential images and matched the image, and measured the movement range of the affected side diaphragm, skin markers and solid tumor centre point. To analyze the correlation between the displacement of tumor centre opoint and the affected side diaphragm, skin markers, lung vital capacity, respiratory cycle and the maximum diameter of tumor.Results:Without statistical significance, there were only six cases measured of the tumor displacement in X axis. The movement range of tumor centre point was (0.84±0.44) mm in Y axis and (0.25±0.18) mm in Z axis. The range of the affected side diaphragm, skin marker, respiratory cycle, vital capacity and the tumor maximum diameter were (1.42±0.44)cm, (0.22±0.09)cm, (3.08±1.22) S, (2.95±0.39) L and (4.41±0.93) cm. There were positive correlations among the affected side diaphragm, respiratory cycle and the displacement of tumor centre point in Y axis; a regression equation can be obtained: Y=-0.228+0.45X1+0.139X2 (X1:the affected side diaphragm, X2:the respiratory cycle)。The displacement of tumor centre point was only positively correlated with the skin markers in Z axis; a regression equation was obtained:Z= 1.136X(X:the skin markers).Conclusion:Based on the X-ray stimulator, applying Photoshop software and Viewletcam software, replacing the movement of CTV by the movement of GTV, the movement range of tumor centre point were accurately measured. The linear equations in Y and Z axes were established, which is a kind of simple and speedily method for drawing the outline of ITV. |
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