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The Diagnosis Of BV Set To Bacterial Vaginosis And Analysis Of The Clinical Feactures And Relation Factors For Bacterial Vaginosis

Posted on:2011-05-12Degree:MasterType:Thesis
Country:ChinaCandidate:Y Q HuangFull Text:PDF
GTID:2144360305978683Subject:Obstetrics and gynecology
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Bacterial vaginosis (BV) is one of the most common vaginal infections in women of reproductive age, in normal vagina there is a group of microorganisms (Gardnerella Prevost bacteria, Streptococcus digestion, purple single intracellular bacteria, dynamic bending mycoplasma bacteria and human nature, etc.), when which abnormal increase and H2O2 generated Lactobacillus decrease or disappeare, resulting in vaginal microbial the clinical syndrome, a group of disorders. The infection rate of BV is reported different in different parts, usually 10%~40%. It is easy to cause a variety of Obstetrics and Gynecology complications, which seriously impact on women's reproductive health. Searching for objective, accurate and simple diagnostic methods, understanding the clinical characteristics of BV, which is of great significance on correct diagnosis of BV, reduce the complications. In this study, the diagnosis of BV and its clinical features were analyzed.Section I The diagnosis of BV set to bacterial vaginosisObjective To evaluate the sensitivity and specificity of each indicator in the Amsel method; the Amsel method as gold standard, to evaluate sensitivity and specificity of the BV set and BV set+clue cells.Methods with paired design,468 cases who went to see the doctor from May 2009 to September 2009 in Second Clinical Hospital of Shanxi Medical University, respectively, adopt BV set and the Amsel to detect.Results1.With the Amsel method 158 cases of patients were detected, the positive rate was 33.8%; with the BV set method 155 cases of patients were detected, the positive rate was 33.1%; with BV set method+clue cells 157 cases of patients were detected, the positive rate was 33.5%, the Kappa coefficient of the three methods were more than 0.7.2. With sensitivity, specificity, Roc area under the curve evaluation method of the four indicators of the Amsel method, the best indicator was clue cells, followed by ammonium test.3. To Amsel method as the gold standard, BV set method and the BV set method+clue cells The sensitivity, specificity and ROC area under the curve of the two method respectively, BV set method: 96.2%,99.0%,0.976, BV set + clue cells:98.7%,99.7%,0.992.Conclusion The BV Set method compared with the Amsel method has high sensitivity and specificity of strong, simple, rapid, and simple equipment and, for the clinical diagnosis of bacterial vaginosis to provide a new frame of reference. BV set + clue cells method can improve the diagnosis of BV.SectionⅡAnalysis of the clinical feactures and relation factors for bacterial vaginosisObjective To evaluate the clinical features and risk factors of bacterial vaginosis (BV).Methods The study was designed as a prospective case-controlled study. Case group include 201 BV pationts, and control group consisted of 310 normal women.Results The mean age of BV was (35.13±9.15), abnormal vaginal discharge (increase or smell) were 139 cases (69.2%), outside the Yin Yang in 97 cases (48.3%), lower abdominal pain in 48 (23.9%),32 cases of patients (15.9%) are asymptomatic. Univariate analysis showed that the use of non-menstrual use pads, bathroom type, history of vaginitis, mixed infection, IUD, condoms, underwear and other clothing with the washing was correlated with BV; Multivariate analysis showed that non-menstrual Using pads (P= 0.028) and sexually frequent (P= 0.025) increase the risk of occurrence of BV; use of condoms (P= 0.023) and use of family bathroom (P= 0.013) can lower the risk of BV.Conclusion The prevalence of bacterial vaginosis is found in women during their reproductive age. Discharge and odor are the main complaints, however some women are asymptomatic. Non-menstrual period using pads and sex frequent are risk factors for BV, family bathroom and use of condoms are the protective factors.
Keywords/Search Tags:Bacterial vaginosis, SAG activity, Amsel method, leucorrhea peculiar smeu, vaginal secretion increase
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