| Objective:To have a preliminary understanding of four common vaginitis pathogen distribution in vaginal of women in the various pregnancy periods,from checking cervical tube and vaginal secretions of the various pregnancy periods and normal women and analysising significantly.Methods:We selected 156 prenatal care women in our hospital from2008.11 to 2009.6 as samples (pregnant women group), aged 20-40 years, mean 29.98 of them were in first trimester (early pregnancy group, gestational age<12 weeks),49 women in second trimester (mid-pregnancy group,16 weeks< gestational age<24 weeks), and 52 women in last trimester (late pregnancy group,gestational age>29 weeks). In addition, we selected 50 health care women (non-pregnant women group)in the same phase in our hospital as contrast as well, aged 22-45 years, mean 30.28.In almost all cases in group 2 weeks without vaginal sex life, lavage and unused antibiotics and other performance-enhancing drugs. Patients were enrolled in without asexual life and vaginal lavage, antibiotics and hormones drugs are not used in the last 2 weeks. All selected cases, get vagina smear and cervical tube secretions:(1)Take the cervix cervical tube secretions, gram stain, under a microscope to find gram-negative diplococcus in neutrophils was diagnosed Gonorrhea. (2) Take vaginal secretions directly,do saline wet sheet, under a microscope find trichomonas vaginalis for diagnosis of Trichomonas vaginalis Vaginitis (TV). (3) Take vaginal smears directly, gram stain, under a microscope find Candidid albicans diagnosed vulvovaginal candidiasis (VVC); under a microscope at each high-power lens perspective find the typical form of Lactobacillus≤5, two or more other forms of bacteria (gram-negative small bacilli, curved bacilli or gram-positive cocci)≥6, that's the diagnosis of bacterial vaginosis (BV).Using the SPSS 13.0 statistical software does statistical analysis of data on pregnant women group and non-pregnant women group,each pregnancy group and non-pregnant women group respectively, among all pregnancy group the same pathogen detection rate of vaginitis lineχ2 test, and different vaginal pathogens in each pregnancy group rowsχ2 test, P<0.05 was considered statistically significant, that is, between the two groups was statistically significant difference in detection rate.Results:1. All cases were not detected in Neisseria Gonorrheae.2. Early pregnancy group and mid-pregnancy group wasn't detected Trichomonas one case was detected in late pregnancy group. The detection rate of TV:pregnant women group 0.6%(1/ 156), non-pregnant women group 2.0%(1/50), lineχ2 test, P>0.05, had no statistically significant difference.3. The detection rate of VVC:pregnant women group 7.7%(12/156), early pregnancy group 3.6%(2/55), mid-pregnancy group 12.2%(6/49), late pregnancy group 7.7% (2/52),non-pregnant women group 4.0%(2/50). Each group line x2 test,the pregnant women group compared with the non-pregnant women group, P>0.05, had no statistically significant difference; each pregnancy group compared with non-pregnant group respectively,P> 0.05, had no statistically significant difference. Comparison among the various pregnancy group, P>0.05, had no statistically significant difference.4. The detection rate of BV:pregnant women group 23.1%(36/156), early pregnancy group 27.3%(15/55), mid-pregnancy group 18.4%(9/49), late pregnancy group 23.1%(12/52), non-pregnant women 8.0%(4/50). Each group lineχ2 test, the pregnant women group compared with the non-pregnant women group, P<0.05, had statistically significant difference; The early pregnancy group and the late pregnancy group compared with non-pregnant women group respectively, P＜0.05, had statistically significant difference;The mid-pregnancy group compared with the non-pregnant women group, P>0.05, had no statistically significant difference; Comparison among the various pregnancy group, P>0.05, had no statistically significant difference.5. The detection rate of BV, VVC in the early pregnancy group and the late pregnancy group lineχ2 test, P<0.05, had statistically significantly difference; The detection rate of BV, VVC in the mid-pregnancy group lineχ2 test, P> 0.05, had no statistically significantly differences.Conclusion:1. The detection rate of VVC in the pregnant women group was slightly higher than the non-pregnant women group (P>0.05), the early pregnancy group was slightly lower than the non-pregnant group (P>0.05), both the mid-pregnancy group and the late pregnancy group was slightly higher than the non-pregnant women group (P>0.05), there were no significant differences among the various pregnancy group.2. The detection rate of BV in the pregnant women group was significantly higher than the non-pregnant women group, the early pregnancy group was significantly higher than the non-pregnant women group, there were no significant differences between the mid-pregnancy group and the non-pregnant women group, so dose the various pregnancy group.3. In the early pregnancy group and the late pregnancy group the detection rate of BV is higher than VVC. There were no significant differences in the mid-pregnancy group.4. The detection rate of TV in the pregnant women group and non-pregnant group had no significant difference. |
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