Clinical Research On Risk Factors Of Microbleeds With Cerebral Infarction

Objective:To assess the value of susceptibility weighted imaging(SWI) in the diagnosis of intracranial hemorrhage(CMBs) and detect microbleeds in the aged with lacunar infarction. So we gain the relation between CMBs and risk factors of lacunar infarction.Methods:Colleted 82 cases of lacunar infarction in our hospital from 2010 to 2011, Summarized and analyzed their clinical and pathological features, The number,location and frequency of microbleeds and location of lacunar infarction were evaluated. Otherwise, we recorded blood pressure, blood fat, blood sugar, previous stroke history and use of aspirin for patients and explored the relation between microbleeds and these factors.Results:CMBs was founded in 22 cases of lacunar infarction group and 6 cases of healthy elder. Slight,moderate, severe degree of microbleeds were founded in lacunar infarction group. Only slight microbleeds were seen in healthy elder. Incidence and grade of microbleeds were significantly different in two groups.There Was a correlation between the number of CMBs and thenumber of lacunar infarction. Microbleeds were more prevalent with previous stroke history. There were no significant relationship demonstrated between microbleeds and diabetes mellitus, use of aspirin(p<0.05)and hypertension. SWI was significantly high in lacunar infarction patients. There were clearly significant relationships demonstrated between microbleeds and number of lacunar infarction.Conclusion:SWI was a new sensitive sequence in detecting CMBs. It Was vital significance in anticoagulation therapy, predicting for hemorrhage in lacunar infarction patients with CMBs. It Was revealed that the frequency of microbleeds was significantly high in lacunar infarction patients. There were clearly significant relationships demonstrated between microbleeds and number of lacunar infarction, previous stroke history.