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Study Of Multiplanar Spiral Computer Tomography Angiography In Intracranial Unruptured Aneurysms

Posted on:2012-08-09Degree:MasterType:Thesis
Country:ChinaCandidate:Y F WangFull Text:PDF
GTID:2154330332499612Subject:Clinical Medicine
Abstract/Summary:PDF Full Text Request
Intracranial aneurysm is like the abnormal tumor on intracranial aneurysm wall. It is the great harm of clinical cerebrovascular disease. Intracranial aneurysms often cause SAH (Subarachnoid Hemorrhage, SAH), which has high morbidity and mortality, and the survivors often get the irreversible brain damage. Most of the smaller volume unbroken intracranial aneurysms have no clinical symptoms, in which the symptoms are not found, so patients rarely come to hospital during that time. However, once the aneurysm rupture causing subarachnoid hemorrhage, patients showed the symptoms of severe headache, nausea, Vomiting and other symptoms. After that, they go to hospital and found intracranial aneurysms. Unruptured intracranial aneurysms mean no history of bleeding aneurysm or aneurysm wall pathology that is not totally ruptured.With the development of medical imaging, CTA (Computer Tomography Angiography) is widely used in the diagnosis and evaluation of intracranial aneurysms, in which more and more unruptured aneurysms were detected.To study the unruptured intracranial aneurysm characteristics, and explore the appropriate treatment and methods, this paper base on multiple aneurysms experimental objects, use the way of multi-slice spiral CT angiography, compare and analyze the size, shape, position, angle and other characteristics between ruptured aneurysms and unruptured broken aneurysms, find the differences between ruptured aneurysm and unbroken aneurysm, and summary the morphological features of ruptured aneurysm.Multi-layer spiral CTA, which is good at non-invasive, short examination time, higher spatial resolution and so on, is widely used in clinical examination. MSCTA shows the excellent three-dimensional imaging of vessel through powerful workstations and advanced image processing technology. This paper analyzes 30 patients, who are diagnosed multiple intracranial aneurysms by subarachnoid hemorrhage, with dual source spiral CTA line inspection. Examine objects contain 8 males and 22 females, whose age from 37 to 73 and the average age is 54.47±9.67 years old. There are totally 66 aneurysms, which contain 34 ruptured aneurysms,2 were 3 cases of multiple aneurysms aneurysms,32 unbroken aneurysms. In the 30 patients,2 were 4 cases of multiple and the rest were 2 cases of multiple aneurysms each. All patients had subarachnoid hemorrhage by CT examination, clinical manifestations of sudden headache, nausea, vomiting, neck stiffness, and even unconsciousness and so on. The study is divided into two groups, the first group is unbroken aneurysm group, the other group is ruptured aneurysm group.All the objects used dual source spiral CT machine (Siemens, Germany), scanning sequence is "Head angiography routine". The baseline scans parallel to canthal lines. Scanning parameters:slice thickness:0.6mm, pitch:0.85, rotation time:0.5sec, scan field of vision:200mm, scan range:3 cervical vertebrae to the skull roof. Scanning conditions:voltage 120kv, current: 230mA. Raw data will be transmitted to SIEMENS workstations after the scan is complete, using MIP (maximum intensity projection), VR (volume rendering), MPR (multiplanner reconstruction) technology to reconstructed image, and make Contrast.Result:1 unbroken aneurysm diameter and rupture of aneurysm diameter were significantly different (t=-3.885, P<0.001), long after its composition than the diameter of the line group chi-square test is still a significant difference. Unbroken aneurysm diameter<3mm is higher potential of ruptured aneurysms. Two groups of wide-necked aneurysms, the top neck ratio, tumor diameter constitute the independent samples T test than the line, P> 0.05, no statistically significant.2 unruptured aneurysm ruptured aneurysm and two aneurysms in different locations were significantly different in the composition,(X2=7.815, P<0.05). The transport segment internal carotid artery below, middle cerebral artery, anterior communicating artery more vulnerable position than other aneurysms, the aneurysm occurred rate to the total number of aneurysms account is 86.36%. Anterior communicating artery, posterior communicating segment carotid artery aneurysms at other locations than the more vulnerable than aneurysm rupture, an exception rate was 73.3%,59.1%.3 constituent ratio of four kinds of unbroken aneurysms and theruptured aneurysms are different, (X2=9.748, P<0.05). Mound aneurysms is not prone to rupture. Lobulated and saccular aneurysm are prone to rupture.4 compare with the two proportions of the aneurysms by the angle, no statistically significant (X2=1.989, P> 0.05).Conclusion:1 patients at 40-60 years old have higher percentage of ruptured intracranial aneurysms, female patients have higher percentage than male. Most patients with hypertension, high blood sugar, smoking, drinking history is the general characteristics of this paper.2 the length of ruptured aneurysm is prompted one of the key indicators, which less than 3mm diameter has low rate of ruptured aneurysm.3 aneurysm position, shape was significantly associated for ruptured aneurysms, anterior communicating artery aneurysms, and posterior communicating artery aneurysms. Hummocky aneurysm rupture is not easy to accur. Lobulated and saccular aneurysm and the aneurysm are prone to rupture.4 the angle of the aneurysm has rupture rate no significant correlation.
Keywords/Search Tags:dual-source spiral CT, CT angiography, image quality, intracranial aneurysm, rupture factors
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