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Clinical Application Of Susceptibility Weighted Imaging In Brain Tumors

Posted on:2012-07-18Degree:MasterType:Thesis
Country:ChinaCandidate:S XuFull Text:PDF
GTID:2154330332499650Subject:Medical imaging and nuclear medicine
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Objective : To assess the clinical value of susceptibility weighted imaging(SWI)in brain neoplasms,and to compare the detection rate of conventional MRI with T1WI enhancement of brain tumors and conventional MRI with SWI in detecting calcification,intratumoral and new blood vessel within the tumor.Methods:Select 46 cases who had surgery in our hospital for brain tumor and had conventional MRI scanning, enhanced T1WI and SWI scans from March 2010 to March 2011.SWI images acquisition is through post– processing software, and the machine automatically correct the phase diagram and the intensity, then through a relatively close to the minimum intensity projection superimposed levels (minimum instensity projection, MinIP) and other reconstruction techniques, then get the image. Two senior physicians of imaging analyze all the images with double-blind method. Compare the detection rate of calcification,intratumoral and new blood vessel within the tumor. Using SPSS13.0 Statistical software to inspect the data used for statistical inference, technical data by chi square test.And the significance level is 0.05, if P <0.05, that there is statistically significant.Results: Conventional magnetic resonance imaging with enhanced T1WI showe: 22 cases of meningioma which owns 26 lesions showes long T1, long T2 signal intensity, T2WI FLAIR showes high signal . There are areas show long T1, short T2 signal in 2 cases, the boundary is not clear, and there are 5 cases with edema, boundary is not clear, enhanced scan showes lesions significantly enhanced, and there is no enhancement in low signal areas.The signal of 15 cases of glioma is uneven, show mixed long T1, long T2 signal, FLAIR is high signal-based mixed signal,there are 4 lesions which are seen in the short T1, long T2 signal intensity, and there are 13 cases with edema, enhanced scan showed enhancement in lesions, 6 lesions show that there is strip high signal around the tumor.8 cases of pituitary tumors showed long T1, long T2 signal, 2 cases are seen short T1, long T2 signal intensity,enhanced scanning the tumors are heterogeneous enhancement,and one of them shows strip high signal around the tumor.The signal of 1 case of Germinoma is uneven, mixed a long T1, long T2 signal intensity, FLAIR showed high and low signal in the lesion; In the tumor there is long T1, long T2 signal intensity, enhanced MRI lesions is homogeneous enhancement.SWI images show 26 lesions of meningioma, the tumor show slightly higher signal, 5 lesions are seen lower signal in the tumor, the phase map correction show high signal, which are confirmed pathological calcification, 3 cases can be seen strip low signal around the tumor; 15 cases of glioma patients with mixed signals, showing the high signal-based mixed signal, there are 10 patients with low signal within the visible point sheet, in some cases shows high signal around the ring, and one of them shows high signal,the other still show low signal in the phase map correction, 13 lesions are seen the high signal edema, 12 lesions are low signal around the ring; 8 cases of pituitary tumor images showe high signal, 3 cases tumors are seen low signal, border is not clear, correct phase diagram is sitill low signal ,1 of them there is high singal around the ring,we can see around the lesion there are strip low signal in 3 cases.Germinoma shows mixed high signal ,in the tumor there is flake low signal, the border is not clear, correct phase diagram shows part of them is high signal, and part of them still show low signal.Pathologically confirmed, the lesion in 50 cases, there is calcification in 6 cases of meningioma ,1 case of glioma and 1 case of germinoma; there is different forms of iron deposition in 10 patients with glioma, 4 cases of pituitary tumor and 1 case of germ cell tumors; there are enlarged blood vessels in 3 cases of meningioma , 14 cases of glioma and 3 cases of pituitary tumors around the tumor .SPSS17.0 statistical system showed that both the former and the latter the detection rate of lesions and edema was no statistically significant difference (P> 0.05); but the detection rate of the calcification, intratumoral hemorrhage and tumor blood vessel for the latter was significantly higher than the former, there was statistically significant (P <0.05). Conclusion: 1. The conventional magnetic resonance imaging combined with enhanced T1WI and the conventional magnetic resonance imaging combined with SWI images have the similar detection rate of the tumor and edema.2. Conventional magnetic resonance imaging conbined with SWI images show the internal structure of the tumor, such as tumor calcification, intratum- oral hemorrhage, and tumor blood vessels that is better than the conventional magnetic resonance imaging combined with enhanced T1WI.3.Susceptibility weighted imaging in the diagnosis of brain tumors is important.
Keywords/Search Tags:Magnetic resonance imaging, Susceptibility weighted imaging, Brain neoplasms, Calcification, Intratumoral hemorrhage, Neovascularization
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