| Objective:Through the observation of intra-articular injection of hyaluronic acid with iontophoresis Duhuojisheng soup for the treatment of knee osteoarthritis symptoms and signs of improvement, the initial approach to clarify the control mechanism of osteoarthritis of the knee, For the clinical use of Integrative Medicine to provide some basis.Method:60 patients with knee osteoarthritis randomized 1:1 into two groups. Treatment group:30 cases, using intra-articular injection of hyaluronic acid and iontophoresis Duhuojisheng soup treatment, Control group:30 cases, injection of sodium hyaluronate with oral,5 weeks as a course. Treatment end observed patients Nocturnal pain, early morning pain, walking pain, tibial soft knee acid, shaped cold cold extremities etc symptoms improvement. evaluation treatment effect and medication Adverse Reaction and security.Results:The clinical trial of treatment of 60 patients with osteoarthritis of the knee, hyaluronic acid, sodium soup with Chinese medicine Duhuojisheng iontophoresis and sodium hyaluronate with oral administration of 30 cases. Treatment group,30 patients with osteoarthritis of the knee Clinical.5 cases of clinical control, markedly effective in 14 cases, Effective in 9 cases, Ineffective in 2 cases, The total effective rate was 93.33%; Control group of 30 patients the clinical effect,2 cases of clinical control, markedly effective in 5 cases, Effective in 15 cases, Ineffective in 8 cases, The total effective rate was 73.33%, Show that the treatment group and control group had significant effects(P<0.05), treatment group improving clinical symptoms better than control group.Conclusion:hyaluronate with Duhuojisheng iontophoresis treatment of knee osteoarthritis with good clinical efficacy, drug safety is good, no apparent side effects, be widely used in clinical practice. |