Investigation Of The Risk Factors And Endothelial Function Of Brachial Artery About Patient Of Hypertension And Coronary Heart Disease

Objective:To investigate in patients with hypertension with different degree of coronary heart disease risk factors and brachial artery diameter, to explore the brachial artery endothelial function changes. Methods:The subjects in my line of patients with coronary angiography in 120 cases, all income groups have been clearly diagnosed cases of hypertension, and in accordance with the results of angiography were divided into two groups, high blood pressure with coronary heart disease group, a total of 78 cases, according to coronary artery lesions involving the patients in this group will be divided into 3 groups:1) single lesions; 2) double-vessel group; 3) 3 or more lesions support group; simple hypertension have high blood pressure but normal coronary angiography results, or narrow<50%, a total of 42 cases. Through the brachial artery ultrasonography Neijing basis, after pressure 30S,60S values of the diameter. Results:1) In hypertension merged with coronary heart disease group, the levels of 24hSBP,24hDBP, TG, LDL-C,2hBG, were significantly higher than those in the simple hypertension group (P<0.05), and the level of HDL-C was significantly lower than it in the simple EH group (P<0.05); 2) The prevalence of smoke in hypertension merged with coronary heart disease group were significantly higher than that of simple hypertension group (P<0.05); 3) The injure of endothelial function in hypertension merged with coronary heart disease group were significantly higher than that of simple hypertension group (P<0.05); 4) The different degree of coronary heart disease in hypertension merged with coronary heart disease was positively and significantly correlated with pressure after the 30S,60S value of the diameter of the risk stratification of coronary heart disease-related (all P< 0.05).' Conclusion:Hypertensive patients with coronary heart disease increased with the degree of coronary artery disease, arterial endothelial dysfunction has also increased the risk; the extent of coronary heart disease more emphasis on its smoking levels, triglyceride, low-density lipoprotein values of the greater lower high-density lipoprotein; vascular endothelial function method of ultrasonic testing in the high blood pressure, coronary heart disease and coronary heart disease in patients with hypertension with the severity of coronary vascular lesions have been to judge.