| Object:By analyzing the patients after brain tumor-related perfusion magnetic resonance perfusion weighted imaging indicators of brain tumor patients to understand the changes in blood volume and vascular permeability, magnetic resonance perfusion imaging of brain tumors after diagnosis increased reactivity, and relapse in residual value.Materials and methods:Collected from October 2009 to December 2010 craniotomy in our hospital after surgery of 68 patients with brain tumors, of which 37 cases of male, female 31 cases, aged 14-71 years, mean 56. After the cases were divided into 31 cases of reactive enhancement, residual tumor after the tumor 9 cases,28 cases of tumor recurrence after surgery. Using the Siemens Sonata 1.5T superconducting MR imager, and then click OK in all cases sagittal SE T1WI, axial FSE T2WI, axial FLAIR, axial SE T1WI, magnetic resonance perfusion weighted imaging (PWI), three orientations SE T1WI enhanced. MR perfusion weighted imaging (PWI) fat-suppressed gradient echo sequence selected plane (GE-EPI) techniques. The images in the workstation Functool post-processing software package, derived cerebral blood volume (rCBV) map, cerebral blood flow (rCBF) maps and relative mean transit time (MTT) map, based on contrast sensitivity caused by the magnetization of each pixel the extent of the signal drawn down time-the signal curve. calculated value of rCBV values calculated by the following formula:rCBV max=maximum rCBV lesion/rCBV of contralateral white matter, rCBF values calculated the same way.Results:(1) The PWI performance of reaction in postoperative:CBV and CBF enhancement part of the pseudo-color pictures MRI showed low perfusion area; Time-the performance of the baseline signal curve nearly flat, no first-pass phenomenon. Strengthening the maximum rCBV ratio of an average of 0.66±0.43, maximum rCBF ratios of 0.64±0.43. Group reactivity enhancement after enhancement rCBV and rCBF ratios of an average of, respectively, compared with perfusion parameters in each group, the difference was statistically significant (P<0.05). (2) The PWI performance of residual in postoperative:CBV and CBF enhancement part of the pseudo-color pictures MRI showed high perfusion, time-the performance curves of the baseline signal recovery delay, signal is higher than the contralateral normal white matter decrease. Strengthening the maximum rCBV ratio of an average of 3.50±0.43, maximum rCBF ratio was 3.10±0.60. Postoperative residual tumor group enhanced rCBV and rCBF ratios of an average of reactivity enhancement after enhancement center perfusion group, the difference was significant (P<0.05). (3) the performance of tumor recurrence in the PWI:CBV and CBF enhancement part of the pseudo-color pictures MRI showed high perfusion area, time-the performance curves of the baseline signal recovery delay, decrease the signal significantly higher than the contralateral normal white matter. Strengthening the maximum rCBV ratio of an average of 4.15±1.33, maximum rCBF ratios of 3.85±1.53. Group of tumor recurrence after an average of rCBV and rCBF enhancement ratio of residual tumor after surgery to strengthen central perfusion group, the difference was not significant (P> 0.05). After tumor recurrence group rCBF rCBV values and the highest, followed by tumor residue group, the reaction enhanced group had the lowest.Conclusion:(1) MR perfusion imaging (PWI) noninvasive vascular proliferation in brain tissue reflect the degree of hemodynamic information, perfusion through the analysis of relevant indicators, able to identify brain tumor responses after injury and residues, provide the basis for monitoring tumor recurrence, to improve the postoperative diagnosis, and evaluate the results of operations and the development of treatment programs have important clinical significance. (2) and conventional MRI in combination, can significantly improve diagnostic accuracy, effectively guide the choice of treatment, can help determine prognosis.
|
PDF Full Text Request